KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
13.64
Human Site:
Y1678
Identified Species:
23.08
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
Y1678
L
N
D
T
L
W
V
Y
H
P
S
T
S
L
S
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
H1467
L
N
D
T
H
W
V
H
H
T
I
T
N
L
T
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
F394
Q
A
T
S
A
P
G
F
K
S
A
F
S
P
Y
Dog
Lupus familis
XP_543382
1925
209302
Y1680
L
N
D
T
L
W
V
Y
H
P
S
T
S
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
Y1740
L
N
D
T
L
W
V
Y
H
P
S
T
S
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
A465
E
E
P
S
A
P
A
A
E
A
G
S
V
E
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
F1763
L
N
D
T
L
W
V
F
H
P
S
T
S
F
S
Frog
Xenopus laevis
Q66J90
1938
216239
Y1693
L
N
D
T
L
W
V
Y
H
P
P
T
S
V
Y
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
P1601
T
L
W
V
H
H
P
P
T
N
M
G
S
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
T1410
D
E
L
I
R
H
K
T
G
C
A
R
T
E
G
Honey Bee
Apis mellifera
XP_395451
1406
159180
G1176
S
G
S
A
R
T
E
G
Y
Y
K
V
D
V
R
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
D1277
L
P
D
A
F
Y
E
D
E
E
L
D
G
V
I
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
L1717
L
S
L
T
P
S
I
L
T
A
C
P
D
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
E1083
V
K
K
I
L
N
S
E
K
S
K
Y
L
P
H
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
60
6.6
100
N.A.
100
N.A.
N.A.
0
86.6
80
6.6
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
80
26.6
100
N.A.
100
N.A.
N.A.
13.3
93.3
86.6
13.3
N.A.
13.3
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
15
0
8
8
0
15
15
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
8
0
50
0
0
0
0
8
0
0
0
8
15
0
0
% D
% Glu:
8
15
0
0
0
0
15
8
15
8
0
0
0
15
0
% E
% Phe:
0
0
0
0
8
0
0
15
0
0
0
8
0
8
0
% F
% Gly:
0
8
0
0
0
0
8
8
8
0
8
8
8
0
8
% G
% His:
0
0
0
0
15
15
0
8
43
0
0
0
0
0
8
% H
% Ile:
0
0
0
15
0
0
8
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
8
0
0
0
8
0
15
0
15
0
0
0
0
% K
% Leu:
58
8
15
0
43
0
0
8
0
0
8
0
8
29
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
43
0
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
8
8
0
8
15
8
8
0
36
8
8
0
22
15
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
8
8
8
15
0
8
8
0
0
15
29
8
50
0
29
% S
% Thr:
8
0
8
50
0
8
0
8
15
8
0
43
8
0
15
% T
% Val:
8
0
0
8
0
0
43
0
0
0
0
8
8
22
0
% V
% Trp:
0
0
8
0
0
43
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
29
8
8
0
8
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _