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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD1B All Species: 31.82
Human Site: Y1813 Identified Species: 53.85
UniProt: Q9UPS6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPS6 NP_055863.1 1923 208732 Y1813 A D E M V I E Y V G Q N I R Q
Chimpanzee Pan troglodytes XP_523492 1707 185692 Y1597 A D E M V I E Y V G Q N I R Q
Rhesus Macaque Macaca mulatta XP_001092031 624 66545 L517 L K E Q R T K L L F L R E P D
Dog Lupus familis XP_543382 1925 209302 Y1815 A D E M V I E Y V G Q N I R Q
Cat Felis silvestris
Mouse Mus musculus Q8CFT2 1985 215333 Y1875 A D E M V I E Y V G Q N I R Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510235 695 75024 E588 P T P L P D S E D E E P G L G
Chicken Gallus gallus Q5F3P8 2008 223067 Y1898 A D E M V I E Y V G Q N I R Q
Frog Xenopus laevis Q66J90 1938 216239 Y1828 A D E M V I E Y V G Q N I R Q
Zebra Danio Brachydanio rerio Q1LY77 1844 204122 Y1734 A D E M V I E Y V G Q N I R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001015221 1641 188364 G1533 E M V I E Y V G Q M I R P V V
Honey Bee Apis mellifera XP_395451 1406 159180 Q1299 M V I E Y V G Q M V R P V V A
Nematode Worm Caenorhab. elegans Q18221 1507 171664 Q1400 M I V E Y I G Q T I R S L V A
Sea Urchin Strong. purpuratus XP_791552 1963 220543 Y1853 A D E M V I E Y V G E S V R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q8X0S9 1313 145607 R1206 E Y V G E E V R Q Q I A E L R
Conservation
Percent
Protein Identity: 100 37.3 27.9 91.9 N.A. 87.7 N.A. N.A. 23.1 61.5 55 51 N.A. 24.7 23.9 22.3 21.3
Protein Similarity: 100 50.3 28.8 93.9 N.A. 90.2 N.A. N.A. 26.7 71.1 66.6 63.6 N.A. 39.4 38.6 35.2 35.2
P-Site Identity: 100 100 6.6 100 N.A. 100 N.A. N.A. 0 100 100 100 N.A. 0 0 6.6 80
P-Site Similarity: 100 100 20 100 N.A. 100 N.A. N.A. 13.3 100 100 100 N.A. 6.6 26.6 26.6 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 0 0 0 0 0 0 0 0 8 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 58 0 0 0 8 0 0 8 0 0 0 0 0 8 % D
% Glu: 15 0 65 15 15 8 58 8 0 8 15 0 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 15 8 0 58 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 8 0 65 0 0 0 8 15 0 50 0 0 % I
% Lys: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 8 0 0 0 8 8 0 8 0 8 15 0 % L
% Met: 15 8 0 58 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % N
% Pro: 8 0 8 0 8 0 0 0 0 0 0 15 8 8 0 % P
% Gln: 0 0 0 8 0 0 0 15 15 8 50 0 0 0 58 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 15 15 0 58 8 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 0 15 0 0 0 % S
% Thr: 0 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % T
% Val: 0 8 22 0 58 8 15 0 58 8 0 0 15 22 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 15 8 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _