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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
24.55
Human Site:
S169
Identified Species:
38.57
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S169
P
K
R
R
K
I
T
S
N
C
T
I
G
L
R
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S356
K
K
K
R
R
K
K
S
V
Y
T
V
G
L
R
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
S335
P
K
R
R
K
I
T
S
N
C
T
I
G
L
R
Dog
Lupus familis
XP_851968
435
49703
L115
P
L
L
R
D
F
F
L
S
D
R
H
R
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S169
P
K
R
R
K
I
T
S
N
C
T
I
G
L
R
Rat
Rattus norvegicus
XP_228777
740
83265
S373
P
R
R
R
R
I
A
S
S
F
T
I
G
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
T158
N
C
I
V
Q
A
L
T
H
T
P
L
L
R
D
Chicken
Gallus gallus
O57429
357
40913
C36
F
M
N
S
I
L
Q
C
L
S
N
T
K
E
L
Frog
Xenopus laevis
Q6GNI6
523
60030
T167
P
K
R
R
K
I
T
T
N
C
T
I
G
L
R
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
A152
P
K
R
R
K
I
T
A
N
C
T
I
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
P390
A
R
R
R
L
V
R
P
N
Q
T
I
G
L
R
Honey Bee
Apis mellifera
XP_395389
502
57164
E152
P
R
R
R
R
V
V
E
N
S
T
I
G
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S153
T
R
K
K
V
S
G
S
S
T
I
G
L
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
W170
P
R
D
R
R
E
K
W
T
F
P
L
G
L
R
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
S144
S
G
L
I
N
M
G
S
T
C
F
M
S
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
46.6
100
13.3
N.A.
100
66.6
N.A.
0
0
93.3
93.3
N.A.
53.3
60
N.A.
6.6
P-Site Similarity:
100
66.6
100
20
N.A.
100
86.6
N.A.
26.6
6.6
100
100
N.A.
66.6
80
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
7
7
0
0
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
7
0
40
0
0
0
7
0
% C
% Asp:
0
0
7
0
7
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
7
0
7
0
0
0
0
0
7
7
% E
% Phe:
7
0
0
0
0
7
7
0
0
14
7
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
14
0
0
0
0
7
67
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
0
7
7
7
40
0
0
0
0
7
54
0
0
7
% I
% Lys:
7
40
14
7
34
7
14
0
0
0
0
0
7
0
0
% K
% Leu:
0
7
14
0
7
7
7
7
7
0
0
14
14
67
7
% L
% Met:
0
7
0
0
0
7
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
0
7
0
0
0
47
0
7
0
0
0
0
% N
% Pro:
60
0
0
0
0
0
0
7
0
0
14
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% Q
% Arg:
0
34
54
74
27
0
7
0
0
0
7
0
7
14
67
% R
% Ser:
7
0
0
7
0
7
0
47
20
14
0
0
7
7
0
% S
% Thr:
7
0
0
0
0
0
34
14
14
14
60
7
0
0
0
% T
% Val:
0
0
0
7
7
14
7
0
7
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _