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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
30.3
Human Site:
S215
Identified Species:
47.62
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S215
R
H
R
C
E
M
Q
S
P
S
S
C
L
V
C
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S402
K
H
K
C
I
M
T
S
P
S
L
C
L
V
C
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
S381
R
H
R
C
E
M
Q
S
P
S
S
C
L
V
C
Dog
Lupus familis
XP_851968
435
49703
H161
L
L
H
L
V
W
T
H
A
R
H
L
A
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S215
R
H
R
C
E
M
Q
S
P
S
S
C
L
V
C
Rat
Rattus norvegicus
XP_228777
740
83265
S419
R
H
R
C
E
M
P
S
P
E
L
C
L
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
P204
G
H
R
S
P
H
I
P
Y
R
L
L
H
L
V
Chicken
Gallus gallus
O57429
357
40913
P82
Q
L
L
W
T
S
S
P
N
D
S
V
S
P
S
Frog
Xenopus laevis
Q6GNI6
523
60030
S213
R
H
K
C
E
M
Q
S
P
N
S
C
L
V
C
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S198
R
H
K
C
E
M
Q
S
N
S
C
L
V
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
S436
R
H
D
C
G
S
K
S
S
H
K
C
L
V
C
Honey Bee
Apis mellifera
XP_395389
502
57164
T198
R
H
H
C
P
Q
P
T
R
C
L
V
C
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S199
H
H
C
E
N
E
R
S
R
D
N
C
L
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
P216
Q
H
N
R
D
L
C
P
R
R
T
M
G
L
L
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
I190
F
S
C
A
L
D
K
I
V
H
E
L
Y
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
66.6
100
0
N.A.
100
80
N.A.
13.3
6.6
86.6
53.3
N.A.
53.3
20
N.A.
40
P-Site Similarity:
100
80
100
0
N.A.
100
80
N.A.
20
13.3
100
66.6
N.A.
60
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
7
% A
% Cys:
0
0
14
60
0
0
7
0
0
7
7
54
7
7
54
% C
% Asp:
0
0
7
0
7
7
0
0
0
14
0
0
0
0
0
% D
% Glu:
0
0
0
7
40
7
0
0
0
7
7
0
0
7
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
7
0
0
0
0
0
0
0
7
14
0
% G
% His:
7
80
14
0
0
7
0
7
0
14
7
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
7
7
0
0
0
0
0
0
0
% I
% Lys:
7
0
20
0
0
0
14
0
0
0
7
0
0
0
0
% K
% Leu:
7
14
7
7
7
7
0
0
0
0
27
27
54
14
7
% L
% Met:
0
0
0
0
0
47
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
14
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
14
0
14
20
40
0
0
0
0
7
0
% P
% Gln:
14
0
0
0
0
7
34
0
0
0
0
0
0
0
0
% Q
% Arg:
54
0
34
7
0
0
7
0
20
20
0
0
0
0
0
% R
% Ser:
0
7
0
7
0
14
7
60
7
34
34
0
7
0
7
% S
% Thr:
0
0
0
0
7
0
14
7
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
7
0
0
14
7
54
14
% V
% Trp:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _