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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
29.39
Human Site:
S233
Identified Species:
46.19
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S233
S
L
F
Q
E
F
Y
S
G
H
R
S
P
H
I
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S420
S
L
F
H
A
M
Y
S
G
S
R
T
P
H
I
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
S399
S
L
F
Q
E
F
Y
S
G
H
R
S
P
H
I
Dog
Lupus familis
XP_851968
435
49703
A179
D
A
H
E
F
L
I
A
A
L
D
V
L
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S233
S
L
F
Q
E
F
Y
S
G
H
R
S
P
H
I
Rat
Rattus norvegicus
XP_228777
740
83265
S437
S
L
F
R
E
L
Y
S
G
N
P
S
P
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
E222
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
F
Chicken
Gallus gallus
O57429
357
40913
P100
T
Q
I
Q
R
Y
A
P
R
F
V
G
Y
N
Q
Frog
Xenopus laevis
Q6GNI6
523
60030
S231
T
L
F
Q
E
F
Y
S
G
H
R
S
P
H
I
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
G216
L
F
Q
E
F
Y
S
G
H
R
S
P
H
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
S454
R
L
F
Q
E
F
Y
S
G
S
R
S
P
L
S
Honey Bee
Apis mellifera
XP_395389
502
57164
S216
F
Q
E
F
Y
S
G
S
K
A
P
L
T
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S217
R
V
F
Q
E
F
Y
S
G
I
R
S
V
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S234
C
D
L
D
V
I
F
S
A
M
F
S
G
D
R
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
T208
K
Q
A
S
S
S
S
T
S
T
N
R
Q
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
66.6
100
6.6
N.A.
100
66.6
N.A.
6.6
6.6
93.3
0
N.A.
73.3
6.6
N.A.
73.3
P-Site Similarity:
100
73.3
100
20
N.A.
100
86.6
N.A.
20
26.6
100
13.3
N.A.
73.3
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
14
0
7
7
14
7
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
0
0
0
0
0
14
0
0
7
0
% D
% Glu:
0
0
7
14
47
0
0
7
0
0
0
0
0
7
0
% E
% Phe:
7
7
54
7
14
40
7
0
0
7
7
0
0
0
7
% F
% Gly:
0
0
0
0
0
7
7
7
54
0
0
7
7
0
7
% G
% His:
0
0
14
7
0
0
0
0
7
27
0
0
14
54
7
% H
% Ile:
0
0
7
0
0
7
7
0
0
7
0
0
0
7
40
% I
% Lys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
47
7
7
0
14
0
0
0
7
0
7
7
14
0
% L
% Met:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
14
7
47
0
7
% P
% Gln:
0
20
7
47
0
0
0
0
7
7
0
0
7
0
7
% Q
% Arg:
14
7
0
7
7
0
0
0
7
7
47
7
0
0
14
% R
% Ser:
34
0
0
7
7
14
14
67
7
14
7
54
0
0
7
% S
% Thr:
14
0
0
0
0
0
0
7
0
7
0
7
7
7
0
% T
% Val:
0
7
0
0
7
0
0
0
0
0
7
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
14
60
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _