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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
27.58
Human Site:
S328
Identified Species:
43.33
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S328
I
D
P
F
W
D
I
S
L
D
L
P
G
S
S
Chimpanzee
Pan troglodytes
XP_521085
711
79749
S515
I
D
P
C
W
D
I
S
L
D
L
P
G
S
C
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
I478
R
L
E
C
S
G
V
I
S
A
H
C
K
L
H
Dog
Lupus familis
XP_851968
435
49703
S245
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S328
I
D
P
F
W
D
I
S
L
D
L
P
G
S
S
Rat
Rattus norvegicus
XP_228777
740
83265
S532
I
D
P
C
W
D
I
S
L
D
L
P
G
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S291
I
D
P
F
W
D
I
S
L
D
L
P
G
S
S
Chicken
Gallus gallus
O57429
357
40913
L166
E
D
S
R
V
S
D
L
F
V
G
Q
L
K
S
Frog
Xenopus laevis
Q6GNI6
523
60030
S326
I
D
P
F
W
D
I
S
L
D
L
P
G
S
S
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S309
I
D
P
F
W
D
I
S
L
D
L
P
G
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
C533
S
S
H
C
Y
G
Q
C
N
C
I
I
D
Q
I
Honey Bee
Apis mellifera
XP_395389
502
57164
N295
D
V
V
C
Q
A
C
N
G
V
S
T
T
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
S317
I
S
L
D
L
G
P
S
S
S
S
N
S
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
D329
T
T
Y
D
P
F
I
D
I
S
L
T
L
D
S
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
H276
K
Q
C
E
C
I
V
H
T
V
F
E
G
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
86.6
0
13.3
N.A.
100
86.6
N.A.
100
13.3
100
100
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
86.6
6.6
13.3
N.A.
100
86.6
N.A.
100
13.3
100
100
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
7
34
7
0
7
7
0
7
0
7
0
0
14
% C
% Asp:
7
54
7
14
0
47
7
7
0
47
0
0
7
7
7
% D
% Glu:
7
0
7
7
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
34
0
7
0
0
7
0
14
0
0
0
0
% F
% Gly:
0
0
0
0
0
27
0
0
7
0
7
0
54
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
7
0
0
0
7
% H
% Ile:
54
0
0
0
0
7
54
7
7
0
7
7
0
7
7
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% K
% Leu:
0
14
7
7
7
0
0
7
47
0
54
0
14
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% N
% Pro:
0
0
47
0
14
0
7
0
0
7
0
47
7
0
7
% P
% Gln:
0
7
0
0
7
0
7
0
0
0
0
7
0
7
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
14
7
0
7
7
7
60
14
14
14
0
7
54
54
% S
% Thr:
7
7
0
0
0
0
0
0
14
0
0
14
7
0
0
% T
% Val:
0
7
7
0
7
0
14
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
47
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _