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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
20.91
Human Site:
S335
Identified Species:
32.86
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S335
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Chimpanzee
Pan troglodytes
XP_521085
711
79749
C522
S
L
D
L
P
G
S
C
A
T
F
D
S
Q
N
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
H485
I
S
A
H
C
K
L
H
L
P
G
S
S
N
S
Dog
Lupus familis
XP_851968
435
49703
S252
S
T
P
F
W
P
L
S
P
G
S
E
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S335
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Rat
Rattus norvegicus
XP_228777
740
83265
C539
S
L
D
L
P
G
S
C
T
S
F
W
P
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S298
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Chicken
Gallus gallus
O57429
357
40913
S173
L
F
V
G
Q
L
K
S
S
L
T
C
S
E
C
Frog
Xenopus laevis
Q6GNI6
523
60030
S333
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S316
S
L
D
L
P
G
S
S
T
P
F
W
P
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
I540
C
N
C
I
I
D
Q
I
F
T
G
M
L
Q
S
Honey Bee
Apis mellifera
XP_395389
502
57164
D302
N
G
V
S
T
T
I
D
P
F
W
D
I
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
P324
S
S
S
S
N
S
A
P
L
T
S
S
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S336
D
I
S
L
T
L
D
S
M
N
G
F
S
P
A
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
L283
H
T
V
F
E
G
S
L
E
S
S
I
V
C
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
53.3
13.3
13.3
N.A.
100
80
N.A.
100
6.6
100
100
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
60
13.3
13.3
N.A.
100
86.6
N.A.
100
13.3
100
100
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
7
0
0
0
0
0
7
% A
% Cys:
7
0
7
0
7
0
0
14
0
0
0
7
0
7
7
% C
% Asp:
7
0
47
0
0
7
7
7
0
0
0
14
0
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
7
0
0
7
0
7
0
% E
% Phe:
0
7
0
14
0
0
0
0
7
7
47
7
0
0
0
% F
% Gly:
0
7
0
7
0
54
0
0
0
7
20
0
7
0
0
% G
% His:
7
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
7
0
7
7
0
0
0
7
7
0
0
% I
% Lys:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% K
% Leu:
7
47
0
54
0
14
14
7
14
7
0
0
7
34
14
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
0
% M
% Asn:
7
7
0
0
7
0
0
0
0
7
0
0
0
7
7
% N
% Pro:
0
0
7
0
47
7
0
7
14
40
0
0
40
7
7
% P
% Gln:
0
0
0
0
7
0
7
0
0
0
0
0
0
14
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
60
14
14
14
0
7
54
54
7
14
20
14
34
20
54
% S
% Thr:
0
14
0
0
14
7
0
0
40
20
7
0
0
0
0
% T
% Val:
0
0
20
0
0
0
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
7
40
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _