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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
18.79
Human Site:
S345
Identified Species:
29.52
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S345
F
W
P
L
S
P
G
S
E
G
N
V
V
N
G
Chimpanzee
Pan troglodytes
XP_521085
711
79749
R532
F
D
S
Q
N
P
E
R
A
D
S
A
V
S
R
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
S495
G
S
S
N
S
P
A
S
A
S
Q
V
A
G
T
Dog
Lupus familis
XP_851968
435
49703
G262
S
E
G
S
V
V
N
G
E
S
H
V
A
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S345
F
W
P
L
S
P
G
S
E
G
S
V
V
N
G
Rat
Rattus norvegicus
XP_228777
740
83265
R549
F
W
P
M
S
P
G
R
E
S
S
L
N
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S308
F
W
P
L
S
P
G
S
D
G
S
V
V
N
G
Chicken
Gallus gallus
O57429
357
40913
C183
T
C
S
E
C
G
Y
C
S
T
A
F
D
P
F
Frog
Xenopus laevis
Q6GNI6
523
60030
S343
F
W
P
L
S
P
G
S
D
A
G
V
V
N
G
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S326
F
W
P
L
S
P
G
S
D
G
S
V
V
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
V550
G
M
L
Q
S
D
V
V
C
Q
A
C
N
G
V
Honey Bee
Apis mellifera
XP_395389
502
57164
G312
W
D
I
S
L
D
L
G
P
A
A
S
A
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
G334
S
S
S
S
L
H
N
G
D
S
G
L
M
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
R346
G
F
S
P
A
D
C
R
K
N
R
Y
S
G
G
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
Q293
S
I
V
C
P
G
C
Q
N
N
S
K
T
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
20
26.6
13.3
N.A.
93.3
46.6
N.A.
86.6
0
80
86.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
40
26.6
20
N.A.
100
66.6
N.A.
100
0
86.6
100
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
14
14
20
7
20
0
0
% A
% Cys:
0
7
0
7
7
0
14
7
7
0
0
7
0
0
0
% C
% Asp:
0
14
0
0
0
20
0
0
27
7
0
0
7
0
0
% D
% Glu:
0
7
0
7
0
0
7
0
27
0
0
0
0
0
7
% E
% Phe:
47
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% F
% Gly:
20
0
7
0
0
14
40
20
0
27
14
0
0
34
47
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% K
% Leu:
0
0
7
34
14
0
7
0
0
0
0
14
0
0
0
% L
% Met:
0
7
0
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
7
7
0
14
0
7
14
7
0
14
34
0
% N
% Pro:
0
0
40
7
7
54
0
0
7
0
0
0
0
7
7
% P
% Gln:
0
0
0
14
0
0
0
7
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
20
0
0
7
0
0
0
7
% R
% Ser:
20
14
34
20
54
0
0
40
7
27
40
7
7
20
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
7
0
0
7
7
14
% T
% Val:
0
0
7
0
7
7
7
7
0
0
0
47
40
0
7
% V
% Trp:
7
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _