KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
17.27
Human Site:
S357
Identified Species:
27.14
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S357
V
N
G
E
S
H
V
S
G
T
T
T
L
T
D
Chimpanzee
Pan troglodytes
XP_521085
711
79749
P544
V
S
R
D
D
H
I
P
G
I
P
S
L
T
D
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
H507
A
G
T
T
G
R
N
H
T
S
Q
T
T
T
L
Dog
Lupus familis
XP_851968
435
49703
D274
A
G
T
T
T
L
T
D
C
L
R
R
F
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S357
V
N
G
E
S
H
A
S
G
T
T
T
L
T
D
Rat
Rattus norvegicus
XP_228777
740
83265
G561
N
G
E
S
H
I
P
G
V
T
T
L
T
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S320
V
N
G
E
S
H
V
S
G
T
T
T
L
T
D
Chicken
Gallus gallus
O57429
357
40913
L195
D
P
F
W
D
L
S
L
P
I
P
K
K
G
Y
Frog
Xenopus laevis
Q6GNI6
523
60030
S355
V
N
G
E
S
H
V
S
G
T
T
T
L
T
D
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S338
V
N
G
D
S
H
P
S
G
A
T
T
L
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
D562
N
G
V
S
T
T
Y
D
P
F
W
D
I
S
L
Honey Bee
Apis mellifera
XP_395389
502
57164
G324
A
S
G
S
D
S
S
G
P
P
T
S
L
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
D346
M
S
P
P
G
F
D
D
V
P
H
S
L
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
A358
S
G
G
P
S
V
N
A
I
M
P
T
L
S
G
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
D305
T
T
I
D
P
F
L
D
L
S
L
D
I
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
40
13.3
6.6
N.A.
93.3
13.3
N.A.
100
0
100
80
N.A.
0
26.6
N.A.
13.3
P-Site Similarity:
100
66.6
20
13.3
N.A.
93.3
13.3
N.A.
100
0
100
86.6
N.A.
20
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
7
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
7
0
0
20
20
0
7
27
0
0
0
14
0
14
60
% D
% Glu:
0
0
7
27
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
14
0
0
0
7
0
0
7
0
0
% F
% Gly:
0
34
47
0
14
0
0
14
40
0
0
0
0
7
7
% G
% His:
0
0
0
0
7
40
0
7
0
0
7
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
0
7
14
0
0
14
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% K
% Leu:
0
0
0
0
0
14
7
7
7
7
7
7
60
7
14
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
14
34
0
0
0
0
14
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
14
7
0
14
7
20
14
20
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
7
0
0
7
0
0
0
0
7
7
0
0
7
% R
% Ser:
7
20
0
20
40
7
14
34
0
14
0
20
0
14
0
% S
% Thr:
7
7
14
14
14
7
7
0
7
34
47
47
14
54
0
% T
% Val:
40
0
7
0
0
7
20
0
14
0
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _