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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
29.7
Human Site:
S456
Identified Species:
46.67
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
S456
Q
Y
Q
Q
P
T
D
S
L
N
N
D
N
K
Y
Chimpanzee
Pan troglodytes
XP_521085
711
79749
V643
G
Q
P
P
T
D
C
V
P
N
E
N
K
Y
S
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
S606
Q
Y
Q
Q
P
T
D
S
L
N
N
D
N
K
Y
Dog
Lupus familis
XP_851968
435
49703
D370
P
T
D
S
L
N
N
D
N
K
Y
S
L
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
S456
Q
Y
Q
Q
P
L
D
S
L
N
N
D
N
K
Y
Rat
Rattus norvegicus
XP_228777
740
83265
S659
Q
L
Q
L
P
T
N
S
G
N
N
E
N
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
S419
Q
Y
Q
Q
P
T
D
S
L
N
N
D
N
K
Y
Chicken
Gallus gallus
O57429
357
40913
A291
A
S
Q
S
C
N
H
A
V
Y
N
L
Y
A
V
Frog
Xenopus laevis
Q6GNI6
523
60030
S454
Q
Y
Q
Q
P
S
D
S
L
H
N
D
N
K
Y
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
S437
Q
Y
Q
Q
P
V
D
S
L
N
N
D
N
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
N666
P
F
M
S
E
K
K
N
A
Y
G
D
F
R
F
Honey Bee
Apis mellifera
XP_395389
502
57164
M428
L
P
K
N
G
E
D
M
A
F
S
D
N
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
T445
H
H
P
R
S
N
R
T
T
T
S
D
N
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S468
G
E
Y
D
S
S
S
S
S
S
P
S
A
E
F
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
G404
K
D
K
H
S
E
N
G
K
V
P
D
I
I
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
6.6
100
0
N.A.
93.3
66.6
N.A.
100
13.3
86.6
93.3
N.A.
6.6
26.6
N.A.
20
P-Site Similarity:
100
13.3
100
6.6
N.A.
93.3
80
N.A.
100
26.6
100
93.3
N.A.
33.3
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
14
0
0
0
7
7
7
% A
% Cys:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
0
7
47
7
0
0
0
67
0
0
0
% D
% Glu:
0
7
0
0
7
14
0
0
0
0
7
7
0
7
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
0
0
7
7
14
% F
% Gly:
14
0
0
0
7
0
0
7
7
0
7
0
0
0
0
% G
% His:
7
7
0
7
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% I
% Lys:
7
0
14
0
0
7
7
0
7
7
0
0
7
47
0
% K
% Leu:
7
7
0
7
7
7
0
0
40
0
0
7
7
0
0
% L
% Met:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
20
20
7
7
47
54
7
60
0
0
% N
% Pro:
14
7
14
7
47
0
0
0
7
0
14
0
0
0
0
% P
% Gln:
47
7
54
40
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
7
0
0
7
0
0
0
0
0
0
14
0
% R
% Ser:
0
7
0
20
20
14
7
54
7
7
14
14
0
0
7
% S
% Thr:
0
7
0
0
7
27
0
7
7
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
7
7
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
7
0
0
0
0
0
0
14
7
0
7
7
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _