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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
20.61
Human Site:
T147
Identified Species:
32.38
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
T147
G
V
G
E
K
F
S
T
W
E
P
T
K
R
E
Chimpanzee
Pan troglodytes
XP_521085
711
79749
T335
G
F
E
D
K
Q
S
T
C
E
T
K
E
Q
E
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
T313
G
A
G
E
K
F
S
T
W
E
P
T
K
R
E
Dog
Lupus familis
XP_851968
435
49703
C95
L
I
N
L
G
N
T
C
F
M
N
C
I
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
T147
G
V
G
E
K
F
S
T
W
E
P
T
K
R
E
Rat
Rattus norvegicus
XP_228777
740
83265
T351
S
L
G
E
K
Y
P
T
W
E
T
T
K
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
C134
R
R
K
I
T
T
N
C
T
I
G
L
R
G
L
Chicken
Gallus gallus
O57429
357
40913
Q16
P
R
S
S
K
V
V
Q
G
L
T
G
L
R
N
Frog
Xenopus laevis
Q6GNI6
523
60030
T145
G
V
G
E
K
Y
S
T
W
E
P
T
K
R
E
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
M130
G
I
G
E
K
Y
S
M
W
E
P
T
K
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
P368
Q
K
S
I
G
W
V
P
W
V
P
T
T
K
E
Honey Bee
Apis mellifera
XP_395389
502
57164
A130
S
F
G
E
F
Y
R
A
W
E
P
T
Q
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
A130
G
I
V
Q
G
F
S
A
W
E
A
T
G
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
S143
A
D
V
V
A
V
R
S
N
K
K
R
R
L
D
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
K124
Y
W
D
D
V
C
T
K
T
M
V
P
S
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
40
93.3
0
N.A.
100
60
N.A.
0
13.3
93.3
80
N.A.
26.6
46.6
N.A.
46.6
P-Site Similarity:
100
60
93.3
26.6
N.A.
100
73.3
N.A.
13.3
13.3
100
93.3
N.A.
40
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
14
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
14
7
0
0
7
0
0
0
% C
% Asp:
0
7
7
14
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
7
47
0
0
0
0
0
60
0
0
7
0
74
% E
% Phe:
0
14
0
0
7
27
0
0
7
0
0
0
0
0
0
% F
% Gly:
47
0
47
0
20
0
0
0
7
0
7
7
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
14
0
0
0
0
0
7
0
0
7
7
0
% I
% Lys:
0
7
7
0
54
0
0
7
0
7
7
7
40
7
0
% K
% Leu:
7
7
0
7
0
0
0
0
0
7
0
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
14
0
0
0
7
0
% M
% Asn:
0
0
7
0
0
7
7
0
7
0
7
0
0
0
7
% N
% Pro:
7
0
0
0
0
0
7
7
0
0
47
7
0
7
0
% P
% Gln:
7
0
0
7
0
7
0
7
0
0
0
0
7
7
7
% Q
% Arg:
7
14
0
0
0
0
14
0
0
0
0
7
14
40
0
% R
% Ser:
14
0
14
7
0
0
47
7
0
0
0
0
7
0
0
% S
% Thr:
0
0
0
0
7
7
14
40
14
0
20
60
7
0
0
% T
% Val:
0
20
14
7
7
14
14
0
0
7
7
0
0
7
0
% V
% Trp:
0
7
0
0
0
7
0
0
60
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
27
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _