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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
38.79
Human Site:
T370
Identified Species:
60.95
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
T370
T
D
C
L
R
R
F
T
R
P
E
H
L
G
S
Chimpanzee
Pan troglodytes
XP_521085
711
79749
T557
T
D
C
L
Q
W
F
T
R
P
E
H
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
T520
T
L
N
A
C
R
F
T
R
P
E
H
L
G
S
Dog
Lupus familis
XP_851968
435
49703
S287
T
R
P
E
H
L
G
S
S
A
K
I
K
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
T370
T
D
C
L
R
R
F
T
R
P
E
H
L
G
S
Rat
Rattus norvegicus
XP_228777
740
83265
R574
D
C
L
R
R
F
T
R
P
E
H
L
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
T333
T
D
C
L
R
R
F
T
R
P
E
H
L
G
S
Chicken
Gallus gallus
O57429
357
40913
M208
G
Y
G
E
V
T
L
M
D
C
L
R
L
F
T
Frog
Xenopus laevis
Q6GNI6
523
60030
T368
T
D
C
L
R
R
F
T
R
P
E
H
L
G
S
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
T351
T
D
C
L
R
R
F
T
R
P
E
H
L
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
T575
S
L
D
L
G
E
T
T
T
H
G
G
V
T
P
Honey Bee
Apis mellifera
XP_395389
502
57164
T337
L
D
C
L
E
R
F
T
R
A
E
H
L
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
T359
D
D
C
L
R
R
F
T
R
P
E
Y
L
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
T371
S
G
C
L
D
F
F
T
R
S
E
K
L
G
P
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
E318
K
D
K
K
K
L
Y
E
C
L
D
S
F
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
86.6
73.3
13.3
N.A.
100
13.3
N.A.
100
6.6
100
100
N.A.
13.3
80
N.A.
86.6
P-Site Similarity:
100
93.3
73.3
26.6
N.A.
100
13.3
N.A.
100
13.3
100
100
N.A.
26.6
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
14
0
0
0
0
0
% A
% Cys:
0
7
60
0
7
0
0
0
7
7
0
0
0
7
0
% C
% Asp:
14
60
7
0
7
0
0
0
7
0
7
0
0
0
0
% D
% Glu:
0
0
0
14
7
7
0
7
0
7
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
14
67
0
0
0
0
0
7
7
0
% F
% Gly:
7
7
7
0
7
0
7
0
0
0
7
7
7
67
0
% G
% His:
0
0
0
0
7
0
0
0
0
7
7
54
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
0
7
7
7
0
0
0
0
0
7
7
7
0
7
% K
% Leu:
7
14
7
67
0
14
7
0
0
7
7
7
74
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
7
54
0
0
0
0
14
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
47
54
0
7
67
0
0
7
0
0
0
% R
% Ser:
14
0
0
0
0
0
0
7
7
7
0
7
0
7
74
% S
% Thr:
54
0
0
0
0
7
14
74
7
0
0
0
0
7
7
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _