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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
34.55
Human Site:
Y258
Identified Species:
54.29
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
Y258
H
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
Chimpanzee
Pan troglodytes
XP_521085
711
79749
Y445
H
A
E
H
L
A
G
Y
R
Q
Q
D
A
H
E
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
Y424
H
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
Dog
Lupus familis
XP_851968
435
49703
N204
A
N
N
P
N
H
C
N
C
I
I
D
Q
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
Y258
H
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
Rat
Rattus norvegicus
XP_228777
740
83265
Y462
H
A
R
H
L
A
G
Y
R
Q
Q
D
A
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
G247
H
C
K
G
D
D
N
G
K
K
A
N
N
P
N
Chicken
Gallus gallus
O57429
357
40913
V125
L
D
G
L
H
G
E
V
N
R
V
L
V
R
P
Frog
Xenopus laevis
Q6GNI6
523
60030
Y256
H
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
E241
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
Y479
H
A
K
H
L
A
G
Y
E
Q
Q
D
A
H
E
Honey Bee
Apis mellifera
XP_395389
502
57164
Q241
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
Y242
H
A
R
H
L
A
G
Y
E
Q
Q
D
A
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
N259
S
W
W
Q
H
S
T
N
L
A
T
Y
E
Q
Q
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
Y233
I
N
Q
N
L
A
G
Y
S
Q
Q
D
A
H
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
86.6
100
6.6
N.A.
100
93.3
N.A.
6.6
0
100
6.6
N.A.
93.3
0
N.A.
100
P-Site Similarity:
100
86.6
100
6.6
N.A.
100
93.3
N.A.
33.3
6.6
100
13.3
N.A.
100
6.6
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
54
0
7
7
60
0
0
0
7
14
7
60
0
0
% A
% Cys:
0
7
0
0
0
0
7
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
7
0
0
0
7
7
67
0
0
0
% D
% Glu:
0
0
7
0
0
0
14
7
40
0
0
0
14
7
60
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
20
% F
% Gly:
0
0
7
7
7
14
60
7
0
0
0
0
0
0
0
% G
% His:
60
7
7
54
14
7
0
0
0
0
0
7
7
60
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% I
% Lys:
0
0
14
0
0
0
0
0
7
7
0
0
0
0
0
% K
% Leu:
7
0
7
14
60
0
0
0
7
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
7
7
7
0
7
14
7
0
0
7
7
0
7
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
0
7
7
0
0
0
7
14
67
60
0
7
7
7
% Q
% Arg:
7
7
40
0
0
0
0
0
14
7
0
0
0
7
0
% R
% Ser:
7
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
7
0
7
0
0
% V
% Trp:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
60
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _