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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
16.67
Human Site:
Y42
Identified Species:
26.19
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
Y42
K
Q
N
L
R
A
I
Y
Q
C
F
V
W
S
G
Chimpanzee
Pan troglodytes
XP_521085
711
79749
Y215
Q
K
N
L
R
L
I
Y
Q
R
F
V
W
S
G
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
Y208
K
Q
N
L
R
A
I
Y
Q
C
F
V
W
S
G
Dog
Lupus familis
XP_851968
435
49703
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
Y42
K
Q
N
L
R
A
I
Y
Q
C
F
V
W
S
G
Rat
Rattus norvegicus
XP_228777
740
83265
Y231
R
Q
E
L
R
V
I
Y
Q
C
F
V
W
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
H39
C
F
T
K
K
H
I
H
E
H
A
K
T
K
R
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6GNI6
523
60030
H47
K
A
K
S
C
I
C
H
M
C
G
A
H
L
N
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
K40
S
A
E
T
R
K
R
K
A
K
S
C
I
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
D264
Y
D
T
F
R
V
I
D
A
Y
F
A
A
C
V
Honey Bee
Apis mellifera
XP_395389
502
57164
K40
S
T
E
A
R
I
R
K
A
V
S
C
L
C
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
N36
V
S
C
S
S
V
E
N
V
K
R
K
A
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
N40
N
N
L
F
R
C
F
N
D
A
R
I
K
I
K
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
P36
Y
I
L
N
H
S
V
P
K
E
K
F
L
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
73.3
100
0
N.A.
100
73.3
N.A.
6.6
0
13.3
6.6
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
86.6
100
0
N.A.
100
80
N.A.
26.6
0
20
6.6
N.A.
20
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
0
20
0
0
20
7
7
14
14
0
7
% A
% Cys:
7
0
7
0
7
7
7
0
0
34
0
14
0
27
0
% C
% Asp:
0
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
7
0
7
7
0
0
0
0
0
% E
% Phe:
0
7
0
14
0
0
7
0
0
0
40
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
34
% G
% His:
0
0
0
0
7
7
0
14
0
7
0
0
7
0
14
% H
% Ile:
0
7
0
0
0
14
47
0
0
0
0
7
7
7
0
% I
% Lys:
27
7
7
7
7
7
0
14
7
14
7
14
7
7
7
% K
% Leu:
0
0
14
34
0
7
0
0
0
0
0
0
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
7
27
7
0
0
0
14
0
0
0
0
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
27
0
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
60
0
14
0
0
7
14
0
0
7
7
% R
% Ser:
14
7
0
14
7
7
0
0
0
0
14
0
0
27
0
% S
% Thr:
0
7
14
7
0
0
0
0
0
0
0
0
7
0
7
% T
% Val:
7
0
0
0
0
20
7
0
7
7
0
34
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% W
% Tyr:
14
0
0
0
0
0
0
34
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _