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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP22
All Species:
41.82
Human Site:
Y517
Identified Species:
65.71
UniProt:
Q9UPT9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPT9
NP_056091.1
525
59961
Y517
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Chimpanzee
Pan troglodytes
XP_521085
711
79749
Y703
S
E
G
Y
L
L
F
Y
H
K
Q
G
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001100993
675
74956
Y667
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Dog
Lupus familis
XP_851968
435
49703
H428
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU02
525
59935
Y517
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Rat
Rattus norvegicus
XP_228777
740
83265
Y720
S
E
G
Y
L
L
F
Y
H
K
Q
V
L
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511206
488
55972
Y480
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Chicken
Gallus gallus
O57429
357
40913
E349
D
A
Y
L
L
F
Y
E
L
A
S
P
S
S
R
Frog
Xenopus laevis
Q6GNI6
523
60030
Y515
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
Y498
S
E
G
Y
L
L
F
Y
H
K
Q
F
L
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
Y727
S
E
G
Y
L
L
F
Y
H
K
N
V
L
E
Y
Honey Bee
Apis mellifera
XP_395389
502
57164
Y489
S
E
G
Y
L
L
F
Y
H
K
Q
I
L
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786312
585
65894
C506
S
E
G
F
I
I
I
C
T
F
S
S
T
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEW0
557
63499
Y528
C
E
C
Y
M
L
F
Y
A
Q
E
T
V
I
Q
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
F464
K
E
Q
A
Y
L
L
F
Y
T
I
R
Q
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
68.5
80.9
N.A.
97.9
58.5
N.A.
86.8
24
91.8
90
N.A.
35.7
60.5
N.A.
55
Protein Similarity:
100
61.3
69.9
82.4
N.A.
99.2
63.9
N.A.
89.5
38.6
95
94
N.A.
47.2
73.5
N.A.
67.8
P-Site Identity:
100
86.6
100
6.6
N.A.
100
86.6
N.A.
100
6.6
100
100
N.A.
86.6
93.3
N.A.
20
P-Site Similarity:
100
86.6
100
26.6
N.A.
100
93.3
N.A.
100
13.3
100
100
N.A.
86.6
93.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.1
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
7
7
0
0
0
0
0
% A
% Cys:
7
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
87
0
0
0
0
0
7
0
0
7
0
7
67
7
% E
% Phe:
0
0
0
7
0
14
74
7
0
7
7
40
0
0
0
% F
% Gly:
0
7
74
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
67
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
7
7
7
0
0
0
7
7
0
7
0
% I
% Lys:
7
0
0
0
0
0
0
0
7
67
0
0
0
0
7
% K
% Leu:
0
0
0
14
80
80
7
0
7
0
0
7
67
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
14
60
0
7
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
14
% R
% Ser:
74
0
0
0
0
0
0
0
0
0
14
7
7
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
7
0
7
7
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
14
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
74
7
0
14
74
7
0
0
0
0
7
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _