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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D2B
All Species:
9.39
Human Site:
Y542
Identified Species:
34.44
UniProt:
Q9UPU7
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPU7
NP_055894.6
963
109880
Y542
L
C
Q
I
E
S
K
Y
L
I
L
L
Q
E
M
Chimpanzee
Pan troglodytes
XP_510522
977
111363
V531
T
I
Q
A
K
D
E
V
I
I
K
L
S
E
G
Rhesus Macaque
Macaca mulatta
XP_001106607
962
109801
Y541
L
C
Q
I
E
S
K
Y
L
I
L
L
Q
E
M
Dog
Lupus familis
XP_545894
845
96944
S437
E
M
K
T
P
V
C
S
E
E
Q
G
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0J8
965
109931
Y544
L
C
Q
V
E
S
K
Y
L
I
L
L
Q
E
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516235
726
83877
N319
E
L
D
R
I
K
D
N
L
Q
G
Y
K
T
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795416
1076
123131
L341
K
D
Q
V
V
M
S
L
T
M
R
V
S
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
97.8
77.8
N.A.
88.8
N.A.
N.A.
64
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
91
98.8
82.2
N.A.
93.4
N.A.
N.A.
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
P-Site Identity:
100
26.6
100
0
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
100
6.6
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
43
0
0
0
0
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
15
0
0
15
15
0
0
0
0
0
0
0
0
% D
% Glu:
29
0
0
0
43
0
15
0
15
15
0
0
0
72
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
15
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
29
15
0
0
0
15
58
0
0
0
0
0
% I
% Lys:
15
0
15
0
15
15
43
0
0
0
15
0
15
0
0
% K
% Leu:
43
15
0
0
0
0
0
15
58
0
43
58
0
0
15
% L
% Met:
0
15
0
0
0
15
0
0
0
15
0
0
0
0
43
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
72
0
0
0
0
0
0
15
15
0
43
0
15
% Q
% Arg:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
15
% R
% Ser:
0
0
0
0
0
43
15
15
0
0
0
0
29
15
0
% S
% Thr:
15
0
0
15
0
0
0
0
15
0
0
0
0
15
0
% T
% Val:
0
0
0
29
15
15
0
15
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _