KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGTPBP1
All Species:
23.64
Human Site:
S278
Identified Species:
47.27
UniProt:
Q9UPW5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPW5
NP_056054.2
1226
138448
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Chimpanzee
Pan troglodytes
XP_001136238
1226
138429
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Rhesus Macaque
Macaca mulatta
XP_001107818
1226
138502
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Dog
Lupus familis
XP_541263
1186
133394
L250
R
G
Y
V
Q
V
L
L
T
I
Y
V
D
W
H
Cat
Felis silvestris
Mouse
Mus musculus
Q641K1
1218
137178
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Rat
Rattus norvegicus
NP_001099570
1219
137094
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233247
1243
139876
A289
V
A
L
D
T
L
A
A
L
L
K
S
K
T
N
Frog
Xenopus laevis
Q6DD21
1225
138763
S280
G
I
L
Q
C
L
K
S
I
T
N
I
K
I
G
Zebra Danio
Brachydanio rerio
Q4U2V3
1153
129774
M234
A
A
L
L
K
S
G
M
N
A
R
R
A
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624180
1081
122639
T162
L
W
L
L
G
Q
I
T
Q
R
D
Q
K
F
V
Nematode Worm
Caenorhab. elegans
NP_491674
1015
116038
L96
F
L
C
R
L
L
H
L
I
F
S
H
F
S
S
Sea Urchin
Strong. purpuratus
XP_001193902
1113
124595
E194
S
G
D
E
N
K
E
E
E
P
Q
K
G
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
92
N.A.
90.5
89.4
N.A.
N.A.
74.3
72.2
63.2
N.A.
N.A.
34.3
26.2
35.6
Protein Similarity:
100
100
99.7
93.7
N.A.
94.4
94.2
N.A.
N.A.
83.9
84.3
77.3
N.A.
N.A.
50.8
42.7
52.1
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
20
80
6.6
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
40
93.3
13.3
N.A.
N.A.
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
0
9
9
0
9
0
0
9
0
9
% A
% Cys:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
0
0
9
0
9
0
9
% D
% Glu:
0
0
0
9
0
0
9
9
9
0
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% F
% Gly:
50
17
0
0
9
0
9
0
0
0
0
0
9
0
50
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% H
% Ile:
0
50
0
0
0
0
9
0
17
9
0
50
0
9
0
% I
% Lys:
0
0
0
0
9
9
50
0
0
0
9
9
67
0
0
% K
% Leu:
9
9
75
17
9
67
9
17
9
9
0
0
0
42
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
9
0
50
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
50
9
9
0
0
9
0
9
9
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
9
9
9
0
0
0
% R
% Ser:
9
0
0
0
42
9
0
50
0
0
9
9
0
9
9
% S
% Thr:
0
0
0
0
9
0
0
9
9
50
0
0
0
9
0
% T
% Val:
9
0
0
9
0
9
0
0
42
0
0
9
0
9
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _