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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC13A
All Species:
27.88
Human Site:
T22
Identified Species:
68.15
UniProt:
Q9UPW8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPW8
NP_001073890
1703
192998
T22
G
A
Q
E
K
F
N
T
Y
V
T
L
K
V
Q
Chimpanzee
Pan troglodytes
XP_001166240
1700
192397
T22
G
S
P
D
K
F
N
T
Y
V
T
L
K
V
Q
Rhesus Macaque
Macaca mulatta
XP_001085980
1606
182441
T19
V
A
S
G
F
F
I
T
N
F
P
A
P
R
K
Dog
Lupus familis
XP_544689
2217
251282
S144
S
A
E
N
Q
A
Q
S
T
H
T
M
P
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q4KUS2
1712
193778
T22
G
A
Q
E
K
F
N
T
Y
V
T
L
K
V
Q
Rat
Rattus norvegicus
Q62768
1735
196338
T22
G
A
Q
E
K
F
N
T
Y
V
T
L
K
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413798
2097
238862
T172
G
S
S
D
G
E
R
T
L
H
T
L
K
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038630
1742
197943
T28
G
P
Q
E
K
F
N
T
Y
V
S
L
K
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726614
2874
320510
P554
Q
S
K
Q
S
P
C
P
P
V
A
L
P
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P27715
2155
245213
S39
G
A
V
D
E
F
N
S
Y
V
T
V
K
L
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
70.8
48.9
N.A.
95.9
94.5
N.A.
N.A.
51.2
N.A.
80.7
N.A.
37.6
N.A.
43.4
N.A.
Protein Similarity:
100
85
80.2
61.9
N.A.
97.4
95.9
N.A.
N.A.
64.9
N.A.
88
N.A.
48.6
N.A.
58
N.A.
P-Site Identity:
100
80
20
20
N.A.
100
100
N.A.
N.A.
33.3
N.A.
86.6
N.A.
13.3
N.A.
60
N.A.
P-Site Similarity:
100
93.3
26.6
53.3
N.A.
100
100
N.A.
N.A.
53.3
N.A.
93.3
N.A.
33.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
10
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
40
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
70
0
0
0
10
0
0
0
0
0
% F
% Gly:
70
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
50
0
0
0
0
0
0
0
70
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
70
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
60
0
10
0
0
0
0
0
10
% N
% Pro:
0
10
10
0
0
10
0
10
10
0
10
0
30
0
0
% P
% Gln:
10
0
40
10
10
0
10
0
0
0
0
0
0
0
60
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% R
% Ser:
10
30
20
0
10
0
0
20
0
0
10
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
70
10
0
70
0
0
0
0
% T
% Val:
10
0
10
0
0
0
0
0
0
70
0
10
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _