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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
22.12
Human Site:
S1250
Identified Species:
48.67
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
S1250
N
V
I
S
E
L
N
S
I
L
Q
Q
M
N
R
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
S1053
K
P
G
E
G
L
D
S
P
M
G
A
K
S
A
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
S1047
K
P
G
E
G
L
D
S
P
M
G
A
K
S
A
Dog
Lupus familis
XP_540798
1938
209283
S1716
N
V
I
S
E
L
N
S
I
L
Q
Q
M
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
S1254
N
V
I
S
E
L
N
S
I
L
Q
Q
M
N
R
Rat
Rattus norvegicus
Q9QX74
1474
158665
S1254
N
V
I
S
E
L
N
S
I
L
Q
Q
M
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
S1166
K
P
G
E
G
L
D
S
P
T
G
T
K
T
A
Chicken
Gallus gallus
XP_426415
1770
194380
S1549
N
V
I
S
E
L
N
S
I
L
Q
Q
M
N
R
Frog
Xenopus laevis
Q52KW0
1292
141161
E1091
E
K
A
T
K
T
G
E
G
L
D
S
P
T
G
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
Q1595
P
E
T
N
S
V
L
Q
H
V
N
K
D
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
I821
S
H
Q
L
D
I
D
I
L
P
P
P
P
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
100
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
20
100
20
26.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
19
0
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
37
0
0
0
10
0
10
0
0
% D
% Glu:
10
10
0
28
46
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
28
0
28
0
10
0
10
0
28
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
46
0
0
10
0
10
46
0
0
0
0
0
0
% I
% Lys:
28
10
0
0
10
0
0
0
0
0
0
10
28
10
0
% K
% Leu:
0
0
0
10
0
73
10
0
10
55
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
19
0
0
46
0
0
% M
% Asn:
46
0
0
10
0
0
46
0
0
0
10
0
0
46
0
% N
% Pro:
10
28
0
0
0
0
0
0
28
10
10
10
19
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
46
46
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% R
% Ser:
10
0
0
46
10
0
0
73
0
0
0
10
0
28
0
% S
% Thr:
0
0
10
10
0
10
0
0
0
10
0
10
0
19
0
% T
% Val:
0
46
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _