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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHANK2 All Species: 18.18
Human Site: S1323 Identified Species: 40
UniProt: Q9UPX8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPX8 NP_036441.2 1470 158822 S1323 P D Y E S R T S G T R R A P S
Chimpanzee Pan troglodytes XP_001174048 1254 134901 M1122 P V V S P T E M N K E T L P A
Rhesus Macaque Macaca mulatta XP_001099714 1248 134508 M1116 P V V S P T E M N K E T L P T
Dog Lupus familis XP_540798 1938 209283 S1789 A D F E S R T S G T R R A P S
Cat Felis silvestris
Mouse Mus musculus Q80Z38 1476 158961 S1327 P D Y E S R T S G P R R A P S
Rat Rattus norvegicus Q9QX74 1474 158665 S1327 P D Y E S R T S G P R R A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507367 1367 148107 L1235 P V V S P T E L S K E L T P S
Chicken Gallus gallus XP_426415 1770 194380 S1622 P D Y D S R T S G A R H A P S
Frog Xenopus laevis Q52KW0 1292 141161 V1160 R A P S P V V V S P A E I I R
Zebra Danio Brachydanio rerio NP_001121819 1800 196374 H1665 A E S L P P H H H T P S P I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786852 1022 110132 S890 S N S N T L R S D V S S S G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 83.6 62.3 N.A. 88.7 89.2 N.A. 77 64.8 62.2 48.4 N.A. N.A. N.A. N.A. 23.2
Protein Similarity: 100 84.8 84 67 N.A. 93.1 93.4 N.A. 82.8 71.5 71.4 58.9 N.A. N.A. N.A. N.A. 38.9
P-Site Identity: 100 13.3 13.3 86.6 N.A. 93.3 93.3 N.A. 20 80 0 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 20 20 93.3 N.A. 93.3 93.3 N.A. 20 86.6 0 13.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 0 0 0 0 0 10 10 0 46 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 46 0 10 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 0 37 0 0 28 0 0 0 28 10 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 46 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 10 10 10 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 19 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 10 0 10 0 0 0 10 19 0 0 % L
% Met: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 10 0 0 0 0 19 0 0 0 0 0 0 % N
% Pro: 64 0 10 0 46 10 0 0 0 28 10 0 10 73 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 46 10 0 0 0 46 37 0 0 10 % R
% Ser: 10 0 19 37 46 0 0 55 19 0 10 19 10 0 64 % S
% Thr: 0 0 0 0 10 28 46 0 0 28 0 19 10 0 10 % T
% Val: 0 28 28 0 0 10 10 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _