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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHANK2 All Species: 21.52
Human Site: S1330 Identified Species: 47.33
UniProt: Q9UPX8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPX8 NP_036441.2 1470 158822 S1330 S G T R R A P S P V V S P T E
Chimpanzee Pan troglodytes XP_001174048 1254 134901 A1129 M N K E T L P A P L S A A T A
Rhesus Macaque Macaca mulatta XP_001099714 1248 134508 T1123 M N K E T L P T P L S A A A A
Dog Lupus familis XP_540798 1938 209283 S1796 S G T R R A P S P V V S P T E
Cat Felis silvestris
Mouse Mus musculus Q80Z38 1476 158961 S1334 S G P R R A P S P V V S P T E
Rat Rattus norvegicus Q9QX74 1474 158665 S1334 S G P R R A P S P V V S P T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507367 1367 148107 S1242 L S K E L T P S P L S A T A A
Chicken Gallus gallus XP_426415 1770 194380 S1629 S G A R H A P S P V V S P T E
Frog Xenopus laevis Q52KW0 1292 141161 R1167 V S P A E I I R D I K P G P L
Zebra Danio Brachydanio rerio NP_001121819 1800 196374 M1672 H H T P S P I M S P P D S G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786852 1022 110132 S897 S D V S S S G S S S S T L T M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 83.6 62.3 N.A. 88.7 89.2 N.A. 77 64.8 62.2 48.4 N.A. N.A. N.A. N.A. 23.2
Protein Similarity: 100 84.8 84 67 N.A. 93.1 93.4 N.A. 82.8 71.5 71.4 58.9 N.A. N.A. N.A. N.A. 38.9
P-Site Identity: 100 20 13.3 100 N.A. 93.3 93.3 N.A. 20 86.6 0 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 40 33.3 100 N.A. 93.3 93.3 N.A. 33.3 86.6 6.6 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 46 0 10 0 0 0 28 19 19 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 28 10 0 0 0 0 0 0 0 0 0 46 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 46 0 0 0 0 10 0 0 0 0 0 10 10 0 % G
% His: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 19 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 28 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 0 0 10 19 0 0 0 28 0 0 10 0 19 % L
% Met: 19 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 28 10 0 10 73 0 73 10 10 10 46 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 46 37 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 55 19 0 10 19 10 0 64 19 10 37 46 10 0 0 % S
% Thr: 0 0 28 0 19 10 0 10 0 0 0 10 10 64 0 % T
% Val: 10 0 10 0 0 0 0 0 0 46 46 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _