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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
16.97
Human Site:
S424
Identified Species:
37.33
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
S424
T
I
K
Q
R
P
S
S
R
C
F
P
A
G
S
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
F271
I
T
E
E
E
R
Q
F
L
A
P
P
M
L
K
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
L266
T
E
E
E
R
Q
F
L
A
P
P
M
L
K
F
Dog
Lupus familis
XP_540798
1938
209283
S799
T
I
K
Q
R
P
T
S
R
C
F
P
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
S428
T
I
K
Q
R
P
T
S
R
C
F
P
A
A
S
Rat
Rattus norvegicus
Q9QX74
1474
158665
S429
T
I
K
Q
R
P
T
S
R
C
F
P
A
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
A381
E
E
E
R
Q
F
L
A
P
P
M
L
K
F
T
Chicken
Gallus gallus
XP_426415
1770
194380
S721
T
I
K
Q
R
P
S
S
R
C
F
P
S
A
T
Frog
Xenopus laevis
Q52KW0
1292
141161
I310
S
R
I
P
L
S
G
I
T
E
E
E
R
Q
F
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
R780
D
N
S
N
A
E
V
R
V
A
T
V
K
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
H40
E
V
G
E
L
S
L
H
K
G
D
H
V
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
6.6
13.3
80
N.A.
86.6
86.6
N.A.
0
80
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
26.6
93.3
N.A.
93.3
93.3
N.A.
33.3
93.3
6.6
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
19
0
0
28
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
19
19
28
28
10
10
0
0
0
10
10
10
0
10
0
% E
% Phe:
0
0
0
0
0
10
10
10
0
0
46
0
0
10
19
% F
% Gly:
0
0
10
0
0
0
10
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
10
46
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
46
0
0
0
0
0
10
0
0
0
19
10
10
% K
% Leu:
0
0
0
0
19
0
19
10
10
0
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
46
0
0
10
19
19
55
0
10
0
% P
% Gln:
0
0
0
46
10
10
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
0
10
55
10
0
10
46
0
0
0
10
0
10
% R
% Ser:
10
0
10
0
0
19
19
46
0
0
0
0
19
0
37
% S
% Thr:
55
10
0
0
0
0
28
0
10
0
10
0
0
0
19
% T
% Val:
0
10
0
0
0
0
10
0
10
0
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _