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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
14.55
Human Site:
S500
Identified Species:
32
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
S500
L
K
F
T
R
S
L
S
M
P
D
T
S
E
D
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
A347
A
T
R
S
D
T
V
A
T
M
M
R
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
T342
T
R
S
D
T
V
A
T
M
M
R
E
K
G
M
Dog
Lupus familis
XP_540798
1938
209283
R875
G
A
Q
G
A
V
F
R
E
N
L
S
R
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
S504
L
K
F
T
R
S
L
S
M
P
D
T
S
E
D
Rat
Rattus norvegicus
Q9QX74
1474
158665
S505
L
K
F
T
R
S
L
S
M
P
D
T
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
M457
R
S
E
N
V
S
T
M
M
R
D
K
G
M
Y
Chicken
Gallus gallus
XP_426415
1770
194380
S797
L
K
F
T
R
S
L
S
M
P
D
T
S
E
D
Frog
Xenopus laevis
Q52KW0
1292
141161
P386
S
G
T
K
S
P
S
P
A
V
R
S
D
N
V
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
R856
P
P
M
L
K
F
T
R
S
L
S
M
P
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
C116
N
S
D
P
R
I
A
C
V
Q
R
G
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
0
6.6
0
N.A.
100
100
N.A.
20
100
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
20
6.6
N.A.
100
100
N.A.
20
100
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
19
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
0
0
0
0
0
46
0
10
10
37
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
10
10
37
0
% E
% Phe:
0
0
37
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
0
10
10
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
37
0
10
10
0
0
0
0
0
0
10
19
19
0
% K
% Leu:
37
0
0
10
0
0
37
0
0
10
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
10
55
19
10
10
0
10
10
% M
% Asn:
10
0
0
10
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
10
10
0
10
0
10
0
10
0
37
0
0
10
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
10
10
0
46
0
0
19
0
10
28
10
10
0
0
% R
% Ser:
10
19
10
10
10
46
10
37
10
0
10
19
37
0
0
% S
% Thr:
10
10
10
37
10
10
19
10
10
0
0
37
0
0
10
% T
% Val:
0
0
0
0
10
19
10
0
10
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _