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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
14.24
Human Site:
Y437
Identified Species:
31.33
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
Y437
G
S
D
M
N
S
V
Y
E
R
Q
G
I
A
V
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
S284
L
K
F
T
R
S
L
S
M
P
D
T
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
M279
K
F
T
R
S
L
S
M
P
D
T
S
E
D
I
Dog
Lupus familis
XP_540798
1938
209283
R812
V
S
D
M
N
P
W
R
C
E
Q
S
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
Y441
A
S
D
V
N
S
V
Y
E
R
Q
G
I
A
V
Rat
Rattus norvegicus
Q9QX74
1474
158665
Y442
A
S
D
V
N
S
V
Y
E
R
Q
G
I
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
P394
F
T
R
S
L
S
M
P
D
T
S
E
D
I
P
Chicken
Gallus gallus
XP_426415
1770
194380
Y734
A
T
D
M
N
S
M
Y
E
R
Q
G
I
A
V
Frog
Xenopus laevis
Q52KW0
1292
141161
L323
Q
F
L
A
P
P
M
L
K
F
T
R
S
L
S
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
F793
P
R
P
T
S
K
C
F
P
V
S
P
E
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
Y53
E
V
T
A
I
G
E
Y
N
Y
W
Q
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
6.6
0
33.3
N.A.
86.6
86.6
N.A.
6.6
80
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
13.3
33.3
N.A.
93.3
93.3
N.A.
26.6
93.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
19
0
0
0
0
0
0
0
0
0
37
0
% A
% Cys:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
0
0
0
0
10
10
10
0
10
10
10
% D
% Glu:
10
0
0
0
0
0
10
0
37
10
0
10
19
10
0
% E
% Phe:
10
19
10
0
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
37
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
37
10
10
% I
% Lys:
10
10
0
0
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
10
10
10
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
28
0
0
28
10
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
46
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
10
0
10
0
10
19
0
10
19
10
0
10
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
46
10
0
0
0
% Q
% Arg:
0
10
10
10
10
0
0
10
0
37
0
10
0
0
10
% R
% Ser:
0
37
0
10
19
55
10
10
0
0
19
19
28
10
10
% S
% Thr:
0
19
19
19
0
0
0
0
0
10
19
10
0
0
0
% T
% Val:
10
10
0
19
0
0
28
0
0
10
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _