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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DICER1 All Species: 13.94
Human Site: S1632 Identified Species: 23.59
UniProt: Q9UPY3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPY3 NP_085124.2 1922 218682 S1632 S V A S S R S S V L K D S E Y
Chimpanzee Pan troglodytes XP_001154199 1922 218702 S1632 S V A S S R S S V L K D S E Y
Rhesus Macaque Macaca mulatta XP_001100868 1920 218494 S1630 S M A S S R S S V L K D L E Y
Dog Lupus familis XP_537547 1923 218622 S1633 S V A S L R P S V L K D L E Y
Cat Felis silvestris
Mouse Mus musculus Q8R418 1916 216802 Y1633 S A G K D L E Y G C L K I P P
Rat Rattus norvegicus XP_001068155 1918 216871 K1631 S P R S S A G K D L E Y G C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510982 1921 218622 F1632 T T N T Q S S F Y K D M E Y G
Chicken Gallus gallus Q25BN1 1921 218592 L1632 I V N S E P S L Y K D L E Y G
Frog Xenopus laevis NP_001163918 1795 204583 C1527 Y D L H T E Q C I A D K S I A
Zebra Danio Brachydanio rerio Q6TV19 1865 210798 F1593 K I P P R C M F E H P D A E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCU9 2249 255312 G1867 A L G L E Q N G G A Q N G Q L
Honey Bee Apis mellifera NP_001116485 1946 224489 N1655 T P F V K G K N E K G E T I W
Nematode Worm Caenorhab. elegans P34529 1845 210905 S1546 V I Q K D Q K S D V P S P L L
Sea Urchin Strong. purpuratus XP_790894 1850 210427 C1566 A A D L P V S C L Y G Y L K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.3 97 N.A. 93 93.5 N.A. 91.8 92 76.5 79.2 N.A. 27.7 35.8 31.7 43.5
Protein Similarity: 100 99.9 99.7 98.4 N.A. 96.1 96.4 N.A. 95.8 95.9 83.9 85.5 N.A. 44 54.5 49.6 60.7
P-Site Identity: 100 100 86.6 80 N.A. 6.6 26.6 N.A. 6.6 20 6.6 13.3 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 93.3 80 N.A. 6.6 33.3 N.A. 20 20 20 26.6 N.A. 46.6 33.3 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 29 0 0 8 0 0 0 15 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 8 0 15 0 8 0 0 0 8 0 % C
% Asp: 0 8 8 0 15 0 0 0 15 0 22 36 0 0 0 % D
% Glu: 0 0 0 0 15 8 8 0 15 0 8 8 15 36 0 % E
% Phe: 0 0 8 0 0 0 0 15 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 8 8 8 15 0 15 0 15 0 15 % G
% His: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 15 0 0 0 0 0 0 8 0 0 0 8 15 0 % I
% Lys: 8 0 0 15 8 0 15 8 0 22 29 15 0 8 0 % K
% Leu: 0 8 8 15 8 8 0 8 8 36 8 8 22 8 22 % L
% Met: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 15 0 0 0 8 8 0 0 0 8 0 0 0 % N
% Pro: 0 15 8 8 8 8 8 0 0 0 15 0 8 8 8 % P
% Gln: 0 0 8 0 8 15 8 0 0 0 8 0 0 8 8 % Q
% Arg: 0 0 8 0 8 29 0 0 0 0 0 0 0 0 8 % R
% Ser: 43 0 0 43 29 8 43 36 0 0 0 8 22 0 0 % S
% Thr: 15 8 0 8 8 0 0 0 0 0 0 0 8 0 0 % T
% Val: 8 29 0 8 0 8 0 0 29 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 0 0 0 0 8 15 8 0 15 0 15 29 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _