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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
13.94
Human Site:
S1632
Identified Species:
23.59
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
S1632
S
V
A
S
S
R
S
S
V
L
K
D
S
E
Y
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
S1632
S
V
A
S
S
R
S
S
V
L
K
D
S
E
Y
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
S1630
S
M
A
S
S
R
S
S
V
L
K
D
L
E
Y
Dog
Lupus familis
XP_537547
1923
218622
S1633
S
V
A
S
L
R
P
S
V
L
K
D
L
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
Y1633
S
A
G
K
D
L
E
Y
G
C
L
K
I
P
P
Rat
Rattus norvegicus
XP_001068155
1918
216871
K1631
S
P
R
S
S
A
G
K
D
L
E
Y
G
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
F1632
T
T
N
T
Q
S
S
F
Y
K
D
M
E
Y
G
Chicken
Gallus gallus
Q25BN1
1921
218592
L1632
I
V
N
S
E
P
S
L
Y
K
D
L
E
Y
G
Frog
Xenopus laevis
NP_001163918
1795
204583
C1527
Y
D
L
H
T
E
Q
C
I
A
D
K
S
I
A
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
F1593
K
I
P
P
R
C
M
F
E
H
P
D
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
G1867
A
L
G
L
E
Q
N
G
G
A
Q
N
G
Q
L
Honey Bee
Apis mellifera
NP_001116485
1946
224489
N1655
T
P
F
V
K
G
K
N
E
K
G
E
T
I
W
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
S1546
V
I
Q
K
D
Q
K
S
D
V
P
S
P
L
L
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
C1566
A
A
D
L
P
V
S
C
L
Y
G
Y
L
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
86.6
80
N.A.
6.6
26.6
N.A.
6.6
20
6.6
13.3
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
6.6
33.3
N.A.
20
20
20
26.6
N.A.
46.6
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
29
0
0
8
0
0
0
15
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
8
0
15
0
8
0
0
0
8
0
% C
% Asp:
0
8
8
0
15
0
0
0
15
0
22
36
0
0
0
% D
% Glu:
0
0
0
0
15
8
8
0
15
0
8
8
15
36
0
% E
% Phe:
0
0
8
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
0
8
8
8
15
0
15
0
15
0
15
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
15
0
0
0
0
0
0
8
0
0
0
8
15
0
% I
% Lys:
8
0
0
15
8
0
15
8
0
22
29
15
0
8
0
% K
% Leu:
0
8
8
15
8
8
0
8
8
36
8
8
22
8
22
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
8
0
0
0
8
0
0
0
% N
% Pro:
0
15
8
8
8
8
8
0
0
0
15
0
8
8
8
% P
% Gln:
0
0
8
0
8
15
8
0
0
0
8
0
0
8
8
% Q
% Arg:
0
0
8
0
8
29
0
0
0
0
0
0
0
0
8
% R
% Ser:
43
0
0
43
29
8
43
36
0
0
0
8
22
0
0
% S
% Thr:
15
8
0
8
8
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
29
0
8
0
8
0
0
29
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
8
15
8
0
15
0
15
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _