KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
30.3
Human Site:
T1289
Identified Species:
51.28
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
T1289
S
I
G
Y
S
S
R
T
L
G
P
N
P
G
L
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
T1289
S
I
G
Y
S
S
R
T
L
G
P
N
P
G
L
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
T1287
S
I
G
Y
S
S
R
T
L
G
P
N
P
G
L
Dog
Lupus familis
XP_537547
1923
218622
T1290
C
P
G
Y
S
S
R
T
L
G
P
N
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
T1289
S
V
G
Y
S
S
R
T
L
G
P
N
P
G
L
Rat
Rattus norvegicus
XP_001068155
1918
216871
T1289
S
V
G
H
S
S
R
T
L
G
P
N
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
T1290
S
N
E
Y
S
S
K
T
L
G
P
N
P
G
L
Chicken
Gallus gallus
Q25BN1
1921
218592
T1290
S
S
G
Y
S
S
K
T
L
G
P
N
P
G
L
Frog
Xenopus laevis
NP_001163918
1795
204583
A1184
L
T
N
G
N
W
E
A
E
S
G
A
C
F
Q
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
E1251
T
S
T
P
A
P
S
E
T
S
S
E
D
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
D1493
H
H
N
Y
S
S
D
D
D
D
V
A
D
D
I
Honey Bee
Apis mellifera
NP_001116485
1946
224489
E1288
I
L
D
L
L
E
T
E
K
N
S
D
E
I
L
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
R1203
L
L
K
Q
A
K
E
R
L
E
A
L
E
M
S
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
E1223
K
E
M
E
R
A
A
E
L
E
V
R
T
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
80
86.6
0
0
N.A.
20
6.6
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
86.6
93.3
6.6
13.3
N.A.
26.6
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
8
8
0
0
8
15
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
8
0
0
0
8
8
8
8
0
8
15
8
0
% D
% Glu:
0
8
8
8
0
8
15
22
8
15
0
8
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
50
8
0
0
0
0
0
58
8
0
0
58
0
% G
% His:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
22
0
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
8
0
8
0
0
8
15
0
8
0
0
0
0
0
8
% K
% Leu:
15
15
0
8
8
0
0
0
72
0
0
8
0
0
65
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
15
0
8
0
0
0
0
8
0
58
0
8
0
% N
% Pro:
0
8
0
8
0
8
0
0
0
0
58
0
58
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
43
8
0
0
0
8
0
0
8
% R
% Ser:
50
15
0
0
65
65
8
0
0
15
15
0
0
0
8
% S
% Thr:
8
8
8
0
0
0
8
58
8
0
0
0
8
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _