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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A11
All Species:
20.3
Human Site:
S231
Identified Species:
37.22
UniProt:
Q9UPY5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY5
NP_055146.1
501
55423
S231
A
F
S
G
R
D
S
S
I
T
R
L
P
L
A
Chimpanzee
Pan troglodytes
XP_001136312
494
54433
S231
A
F
S
G
R
D
S
S
I
T
R
L
P
L
A
Rhesus Macaque
Macaca mulatta
XP_001086173
501
55518
S231
A
F
S
G
R
D
S
S
I
T
R
L
P
L
A
Dog
Lupus familis
XP_540941
488
53551
N231
A
F
S
G
R
G
A
N
I
M
G
L
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR6
502
55438
S231
A
F
S
G
R
D
T
S
L
M
G
L
P
L
A
Rat
Rattus norvegicus
Q9R0S5
512
55623
A227
S
F
E
G
S
S
F
A
M
G
D
I
A
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520121
442
49024
A186
Y
S
G
M
Y
A
Y
A
G
W
F
Y
L
N
F
Chicken
Gallus gallus
XP_426289
516
56714
S229
A
F
S
G
N
D
A
S
I
M
G
L
P
L
A
Frog
Xenopus laevis
A1L3M3
510
55983
D227
S
F
A
G
S
S
W
D
A
G
D
I
S
L
G
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
S210
Y
S
A
L
F
S
Y
S
G
W
D
T
L
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395404
489
53819
Q219
P
M
N
G
T
N
T
Q
P
G
Y
I
A
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784464
501
54880
S219
S
F
D
T
S
K
F
S
F
R
T
F
P
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
T252
F
E
G
T
E
T
A
T
A
Y
G
I
V
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.5
92
N.A.
89.2
43.3
N.A.
78.4
81
41.9
44.5
N.A.
N.A.
44.5
N.A.
46.9
Protein Similarity:
100
97.2
99.8
95
N.A.
96.2
65
N.A.
82.4
88.5
65
62.8
N.A.
N.A.
64.2
N.A.
66.2
P-Site Identity:
100
100
100
66.6
N.A.
73.3
26.6
N.A.
0
73.3
20
6.6
N.A.
N.A.
20
N.A.
33.3
P-Site Similarity:
100
100
100
80
N.A.
86.6
53.3
N.A.
6.6
80
40
13.3
N.A.
N.A.
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
16
0
0
8
24
16
16
0
0
0
16
0
77
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
39
0
8
0
0
24
0
0
0
0
% D
% Glu:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
70
0
0
8
0
16
0
8
0
8
8
0
0
16
% F
% Gly:
0
0
16
70
0
8
0
0
16
24
31
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
39
0
0
31
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
8
0
0
47
16
77
0
% L
% Met:
0
8
0
8
0
0
0
0
8
24
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
8
0
0
0
0
0
24
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
54
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
39
0
0
0
0
8
24
0
0
0
0
% R
% Ser:
24
16
47
0
24
24
24
54
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
16
8
8
16
8
0
24
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% W
% Tyr:
16
0
0
0
8
0
16
0
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _