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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A11
All Species:
29.7
Human Site:
Y412
Identified Species:
54.44
UniProt:
Q9UPY5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY5
NP_055146.1
501
55423
Y412
A
G
L
I
Y
L
R
Y
K
C
P
D
M
H
R
Chimpanzee
Pan troglodytes
XP_001136312
494
54433
Y412
A
G
L
I
Y
L
R
Y
K
C
P
D
M
H
R
Rhesus Macaque
Macaca mulatta
XP_001086173
501
55518
Y412
A
G
L
I
Y
L
R
Y
K
C
P
D
M
H
R
Dog
Lupus familis
XP_540941
488
53551
Y412
A
G
L
I
Y
L
R
Y
K
R
P
D
M
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR6
502
55438
Y412
A
G
L
I
Y
L
R
Y
K
R
P
D
M
H
R
Rat
Rattus norvegicus
Q9R0S5
512
55623
W408
V
G
Q
L
Y
L
R
W
K
E
P
D
R
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520121
442
49024
I366
P
F
K
V
P
L
F
I
P
A
L
F
S
F
T
Chicken
Gallus gallus
XP_426289
516
56714
Y410
A
G
L
I
Y
L
R
Y
K
R
P
D
M
P
R
Frog
Xenopus laevis
A1L3M3
510
55983
Y408
A
G
Q
I
Y
L
R
Y
K
R
P
E
L
P
R
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
Y390
P
L
K
L
S
L
V
Y
P
I
I
F
C
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395404
489
53819
Y400
S
G
L
L
W
L
R
Y
K
S
P
N
R
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784464
501
54880
W400
A
I
I
P
Y
Y
R
W
K
H
P
E
L
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
W440
A
G
L
L
W
I
Y
W
Q
R
R
Q
G
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.5
92
N.A.
89.2
43.3
N.A.
78.4
81
41.9
44.5
N.A.
N.A.
44.5
N.A.
46.9
Protein Similarity:
100
97.2
99.8
95
N.A.
96.2
65
N.A.
82.4
88.5
65
62.8
N.A.
N.A.
64.2
N.A.
66.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
53.3
N.A.
6.6
86.6
66.6
13.3
N.A.
N.A.
53.3
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
66.6
N.A.
13.3
86.6
80
20
N.A.
N.A.
80
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
24
0
0
8
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
16
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
16
0
8
0
% F
% Gly:
0
77
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
39
0
% H
% Ile:
0
8
8
54
0
8
0
8
0
8
8
0
0
0
8
% I
% Lys:
0
0
16
0
0
0
0
0
77
0
0
0
0
8
0
% K
% Leu:
0
8
62
31
0
85
0
0
0
0
8
0
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
16
0
0
8
8
0
0
0
16
0
77
0
0
31
0
% P
% Gln:
0
0
16
0
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
77
0
0
39
8
0
16
0
77
% R
% Ser:
8
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
8
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
16
0
0
24
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
70
8
8
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _