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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HPS5 All Species: 9.09
Human Site: S545 Identified Species: 33.33
UniProt: Q9UPZ3 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPZ3 NP_009147.3 1129 127449 S545 S L Q A V K E S V S S F V R K
Chimpanzee Pan troglodytes XP_508314 1266 142483 S682 S L Q A V K E S V S S F V R K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542523 1133 127732 S549 S L Q A V K E S V S S F V R K
Cat Felis silvestris
Mouse Mus musculus P59438 1126 126289 K543 L V S L Q A V K D S V S S F V
Rat Rattus norvegicus NP_001129084 1126 126264 K543 L L S L Q A V K D S V S S F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421011 1143 128230 F550 V K E S V S S F V R K T T E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHN9 826 93601 P254 K T A L A T A P A R I Q R P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 N.A. 86.9 N.A. 81.3 80.4 N.A. N.A. 67.1 N.A. N.A. N.A. 22.5 N.A. N.A. N.A.
Protein Similarity: 100 88.7 N.A. 92.4 N.A. 89.9 88.4 N.A. N.A. 78.3 N.A. N.A. N.A. 40.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 6.6 13.3 N.A. N.A. 20 N.A. N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 13.3 13.3 N.A. N.A. 33.3 N.A. N.A. N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 43 15 29 15 0 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % D
% Glu: 0 0 15 0 0 0 43 0 0 0 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 43 0 29 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % I
% Lys: 15 15 0 0 0 43 0 29 0 0 15 0 0 0 58 % K
% Leu: 29 58 0 43 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 15 0 0 0 0 0 15 0 % P
% Gln: 0 0 43 0 29 0 0 0 0 0 0 15 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 29 0 0 15 43 0 % R
% Ser: 43 0 29 15 0 15 15 43 0 72 43 29 29 0 0 % S
% Thr: 0 15 0 0 0 15 0 0 0 0 0 15 15 0 0 % T
% Val: 15 15 0 0 58 0 29 0 58 0 29 0 43 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _