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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
22.73
Human Site:
Y495
Identified Species:
45.45
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
Y495
H
Y
L
K
H
S
R
Y
L
P
G
I
S
I
R
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
Y496
H
Y
L
K
H
S
R
Y
L
P
G
I
S
I
R
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
Y479
H
Y
L
K
H
S
R
Y
L
P
G
I
N
I
R
Dog
Lupus familis
XP_538964
685
76968
Y548
H
Y
L
K
H
S
R
Y
L
P
G
I
N
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
Y492
H
Y
L
K
H
S
R
Y
L
P
G
I
N
I
R
Rat
Rattus norvegicus
Q62726
629
70550
Y492
H
Y
L
K
H
S
R
Y
L
P
G
I
N
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
V489
Q
S
R
Y
L
P
G
V
N
P
K
N
V
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
V163
V
R
T
F
T
H
E
V
V
T
L
W
Y
R
A
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
L495
S
A
L
M
S
K
P
L
A
P
I
G
G
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
N435
Q
L
Q
P
N
M
K
N
G
R
K
V
S
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
D442
A
S
L
D
W
E
D
D
D
D
F
L
K
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L308
I
H
D
L
E
L
R
L
D
N
M
A
A
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
0
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
6.6
13.3
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
9
0
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
9
9
17
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
9
0
50
9
9
9
0
% G
% His:
50
9
0
0
50
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
50
0
50
0
% I
% Lys:
0
0
0
50
0
9
9
0
0
0
17
0
9
0
9
% K
% Leu:
0
9
67
9
9
9
0
17
50
0
9
9
0
9
9
% L
% Met:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
9
9
0
9
34
0
0
% N
% Pro:
0
0
0
9
0
9
9
0
0
67
0
0
0
0
25
% P
% Gln:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
0
59
0
0
9
0
0
0
9
50
% R
% Ser:
9
17
0
0
9
50
0
0
0
0
0
0
25
17
0
% S
% Thr:
0
0
9
0
9
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
17
9
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
50
0
9
0
0
0
50
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _