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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH4
All Species:
13.64
Human Site:
S760
Identified Species:
33.33
UniProt:
Q9UQ05
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ05
NP_036417.1
1017
111693
S760
R
P
R
G
S
L
V
S
L
L
G
E
E
L
P
Chimpanzee
Pan troglodytes
XP_001166613
1017
111671
S760
R
P
R
G
S
L
V
S
L
L
G
E
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001087332
1113
124417
K752
N
K
K
V
G
S
S
K
T
Y
L
G
L
S
L
Dog
Lupus familis
XP_849505
1017
111328
S760
R
P
R
G
S
L
V
S
L
L
G
E
E
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P59111
1102
123258
K746
S
K
K
T
G
S
N
K
T
Y
L
G
L
S
L
Rat
Rattus norvegicus
Q9R1T9
1017
111385
S759
R
P
R
G
S
L
V
S
L
L
G
E
E
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508200
1155
129668
K794
N
K
K
I
G
S
N
K
S
Y
L
G
I
S
L
Chicken
Gallus gallus
Q9PT84
526
59775
P280
A
I
G
N
V
E
R
P
Y
M
E
H
K
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695830
986
111517
E739
S
L
G
N
L
L
G
E
E
L
M
Q
F
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
D786
Q
A
T
L
A
R
Q
D
T
I
D
E
G
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
54.5
92.7
N.A.
54.4
89.6
N.A.
50.8
23.2
N.A.
58.1
N.A.
29.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
66.2
94.8
N.A.
65.8
93.4
N.A.
62.5
35
N.A.
70.2
N.A.
45.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
0
100
N.A.
0
0
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
6.6
100
N.A.
6.6
20
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
10
10
0
10
50
40
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
20
40
30
0
10
0
0
0
40
30
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
30
30
0
0
0
0
30
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
10
10
50
0
0
40
50
30
0
20
40
30
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
20
0
0
20
0
0
20
0
0
0
0
0
0
10
0
% N
% Pro:
0
40
0
0
0
0
0
10
0
0
0
0
0
0
40
% P
% Gln:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
40
0
40
0
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
40
30
10
40
10
0
0
0
0
30
0
% S
% Thr:
0
0
10
10
0
0
0
0
30
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
30
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _