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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNH4 All Species: 20.61
Human Site: T259 Identified Species: 50.37
UniProt: Q9UQ05 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ05 NP_036417.1 1017 111693 T259 G D D D T P I T S R H T L V S
Chimpanzee Pan troglodytes XP_001166613 1017 111671 T259 G D D D T P I T S R H T L V S
Rhesus Macaque Macaca mulatta XP_001087332 1113 124417 T260 G N D D L S T T R S T T V S D
Dog Lupus familis XP_849505 1017 111328 T259 G D D D T P I T S R H T L V S
Cat Felis silvestris
Mouse Mus musculus P59111 1102 123258 T254 G N E D L S T T R S T T V S D
Rat Rattus norvegicus Q9R1T9 1017 111385 T260 G D D D T P I T S R H T L V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508200 1155 129668 T304 G N D D L S T T R S T T V S D
Chicken Gallus gallus Q9PT84 526 59775
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695830 986 111517 A253 A Y S D V E T A G R S T I V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02280 1174 126352 S269 N K T S E D V S L L V V D S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 54.5 92.7 N.A. 54.4 89.6 N.A. 50.8 23.2 N.A. 58.1 N.A. 29.9 N.A. N.A. N.A.
Protein Similarity: 100 99.7 66.2 94.8 N.A. 65.8 93.4 N.A. 62.5 35 N.A. 70.2 N.A. 45.6 N.A. N.A. N.A.
P-Site Identity: 100 100 33.3 100 N.A. 26.6 100 N.A. 33.3 0 N.A. 33.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 100 N.A. 46.6 100 N.A. 46.6 0 N.A. 40 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 40 60 80 0 10 0 0 0 0 0 0 10 0 30 % D
% Glu: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 70 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 40 0 0 0 0 0 10 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 30 0 0 0 10 10 0 0 40 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 30 50 0 0 0 0 0 % R
% Ser: 0 0 10 10 0 30 0 10 40 30 10 0 0 40 50 % S
% Thr: 0 0 10 0 40 0 40 70 0 0 30 80 0 0 0 % T
% Val: 0 0 0 0 10 0 10 0 0 0 10 10 30 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _