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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHDH All Species: 3.94
Human Site: S66 Identified Species: 8.67
UniProt: Q9UQ10 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ10 NP_055290.1 334 36382 S66 E E L A K D P S V E V A Y I G
Chimpanzee Pan troglodytes XP_512808 334 36395 N66 E E L A K D P N V E V A Y I G
Rhesus Macaque Macaca mulatta XP_001112315 408 44331 N66 E E L A K D P N V E V A Y V G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9DBB8 333 36282 N66 E E L A K D P N V E V A Y I A
Rat Rattus norvegicus XP_002725668 333 36244 T66 E E L A K S P T L E V A Y I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKE0 330 36328 D66 E E L A K D P D I D V I Y V G
Zebra Danio Brachydanio rerio Q642M9 334 36548 E66 E E L A E D P E I D V V Y V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608675 335 37267 D68 E E L A K S T D V D V V Y I G
Honey Bee Apis mellifera XP_623497 331 36880 D66 T K L A E D N D I D A V Y I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786234 350 38766 N67 E E L A R D P N V D V V Y I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZ83 362 39544 E71 E S L L E D P E I D A L Y V P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 77.2 N.A. N.A. 78.7 77.2 N.A. N.A. N.A. 51.7 50.5 N.A. 43.2 41.9 N.A. 39.1
Protein Similarity: 100 97.3 79.1 N.A. N.A. 86.5 86.8 N.A. N.A. N.A. 71.8 68.5 N.A. 60 58.3 N.A. 57.4
P-Site Identity: 100 93.3 86.6 N.A. N.A. 86.6 73.3 N.A. N.A. N.A. 66.6 60 N.A. 66.6 40 N.A. 73.3
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 86.6 N.A. N.A. N.A. 86.6 86.6 N.A. 73.3 66.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 23.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 91 0 0 0 0 0 0 19 46 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 82 0 28 0 55 0 0 0 0 0 % D
% Glu: 91 82 0 0 28 0 0 19 0 46 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 37 0 0 10 0 64 0 % I
% Lys: 0 10 0 0 64 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 100 10 0 0 0 0 10 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 37 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 19 0 10 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 55 0 82 37 0 37 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _