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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHDH All Species: 29.09
Human Site: T211 Identified Species: 64
UniProt: Q9UQ10 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ10 NP_055290.1 334 36382 T211 H E T G V D D T V T V L L Q Y
Chimpanzee Pan troglodytes XP_512808 334 36395 T211 H E T G V D D T V T V L L Q Y
Rhesus Macaque Macaca mulatta XP_001112315 408 44331 T211 H E T G V D D T V T V L L Q Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9DBB8 333 36282 T211 H E T G V D D T V S V L L Q Y
Rat Rattus norvegicus XP_002725668 333 36244 T211 H E T G V D D T V S V L L Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKE0 330 36328 T211 H E T G V D E T I S I I L E Y
Zebra Danio Brachydanio rerio Q642M9 334 36548 A211 L D T G V D E A M V V T L K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608675 335 37267 D212 N A E G I D D D V S A T L T Y
Honey Bee Apis mellifera XP_623497 331 36880 S211 N E E G V D Q S A S I S F L Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786234 350 38766 S211 N D D G V D E S Y T T V M K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZ83 362 39544 I222 V L N E A G V I L S C G A S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 77.2 N.A. N.A. 78.7 77.2 N.A. N.A. N.A. 51.7 50.5 N.A. 43.2 41.9 N.A. 39.1
Protein Similarity: 100 97.3 79.1 N.A. N.A. 86.5 86.8 N.A. N.A. N.A. 71.8 68.5 N.A. 60 58.3 N.A. 57.4
P-Site Identity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 60 40 N.A. 40 33.3 N.A. 26.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. N.A. 100 73.3 N.A. 60 60 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 23.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 10 10 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 19 10 0 0 91 55 10 0 0 0 0 0 0 0 % D
% Glu: 0 64 19 10 0 0 28 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 19 % F
% Gly: 0 0 0 91 0 10 0 0 0 0 0 10 0 0 0 % G
% His: 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 10 0 19 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % K
% Leu: 10 10 0 0 0 0 0 0 10 0 0 46 73 10 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % M
% Asn: 28 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 46 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 19 0 55 0 10 0 10 0 % S
% Thr: 0 0 64 0 0 0 0 55 0 37 10 19 0 10 0 % T
% Val: 10 0 0 0 82 0 10 0 55 10 55 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 73 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _