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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
29.09
Human Site:
S157
Identified Species:
45.71
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
S157
T
L
A
L
S
E
N
S
L
T
S
L
P
D
S
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
L145
L
P
A
E
V
G
C
L
V
N
L
M
T
L
A
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
S157
T
L
A
L
S
E
N
S
L
T
S
L
P
D
S
Dog
Lupus familis
XP_535013
582
64867
S157
T
L
A
L
N
E
N
S
L
T
S
L
P
D
S
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
S157
T
L
A
L
S
E
N
S
L
T
S
L
P
D
S
Rat
Rattus norvegicus
Q6AYI5
582
64902
S157
T
L
A
L
S
E
N
S
L
T
S
L
P
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
S157
T
L
A
L
S
E
N
S
L
T
S
L
P
D
S
Chicken
Gallus gallus
Q5F4C4
529
59144
L138
Y
S
N
K
L
Q
S
L
P
A
E
V
G
C
L
Frog
Xenopus laevis
Q8AVI4
577
64082
S159
S
L
T
S
L
P
D
S
L
D
N
L
K
K
L
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
K159
M
L
D
L
R
H
N
K
L
R
E
I
P
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
S217
N
L
A
L
N
E
N
S
L
T
S
L
P
E
S
Honey Bee
Apis mellifera
XP_396017
561
62921
L156
K
S
L
R
V
L
D
L
R
H
N
K
L
S
E
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
E156
L
R
H
N
K
L
T
E
V
P
S
V
I
Y
K
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
L119
L
D
L
R
H
N
K
L
K
E
I
P
E
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
K185
D
L
A
L
S
Q
N
K
L
T
G
S
I
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
6.6
100
93.3
N.A.
100
100
N.A.
100
0
26.6
33.3
N.A.
80
0
6.6
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
20
46.6
40
N.A.
93.3
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
0
0
0
0
0
0
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% C
% Asp:
7
7
7
0
0
0
14
0
0
7
0
0
0
40
0
% D
% Glu:
0
0
0
7
0
47
0
7
0
7
14
0
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
0
% G
% His:
0
0
7
0
7
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
7
14
0
0
% I
% Lys:
7
0
0
7
7
0
7
14
7
0
0
7
7
7
7
% K
% Leu:
20
67
14
60
14
14
0
27
67
0
7
54
7
7
14
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
7
14
7
60
0
0
7
14
0
0
0
0
% N
% Pro:
0
7
0
0
0
7
0
0
7
7
0
7
54
7
0
% P
% Gln:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
14
7
0
0
0
7
7
0
0
0
0
0
% R
% Ser:
7
14
0
7
40
0
7
54
0
0
54
7
0
7
54
% S
% Thr:
40
0
7
0
0
0
7
0
0
54
0
0
7
0
0
% T
% Val:
0
0
0
0
14
0
0
0
14
0
0
14
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _