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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
31.52
Human Site:
S218
Identified Species:
49.52
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
S218
I
K
N
L
S
K
L
S
M
L
S
I
R
E
N
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
L199
D
S
L
T
T
L
Y
L
R
F
N
R
I
T
T
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
S218
I
K
N
L
S
K
L
S
M
L
S
I
R
E
N
Dog
Lupus familis
XP_535013
582
64867
S218
I
K
N
L
S
K
L
S
M
L
S
I
R
E
N
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
S218
I
K
N
L
P
K
L
S
M
L
S
I
R
E
N
Rat
Rattus norvegicus
Q6AYI5
582
64902
S218
V
R
N
L
P
R
L
S
T
L
S
I
R
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
I218
I
K
N
L
S
K
L
I
M
L
S
I
R
E
N
Chicken
Gallus gallus
Q5F4C4
529
59144
T192
P
S
V
V
Y
R
L
T
S
L
A
T
L
Y
L
Frog
Xenopus laevis
Q8AVI4
577
64082
T213
L
K
M
L
P
K
L
T
M
L
S
I
R
E
N
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
I220
I
G
E
L
C
N
L
I
T
L
D
V
A
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
T278
L
R
Q
L
V
N
L
T
M
L
S
L
R
E
N
Honey Bee
Apis mellifera
XP_396017
561
62921
L210
R
E
N
K
I
R
E
L
P
A
G
I
G
K
L
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
T211
P
S
A
I
G
K
L
T
S
L
V
V
C
L
V
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
G173
K
A
L
P
R
G
V
G
K
L
T
L
L
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
T273
I
G
N
M
E
S
M
T
N
L
A
L
S
Q
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
0
100
100
N.A.
93.3
66.6
N.A.
93.3
13.3
73.3
33.3
N.A.
53.3
13.3
20
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
86.6
N.A.
93.3
40
86.6
40
N.A.
80
33.3
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
0
7
14
0
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
7
7
0
7
0
7
0
0
0
0
0
0
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
14
0
0
7
7
0
7
0
0
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
47
0
0
7
7
0
0
14
0
0
0
54
7
0
0
% I
% Lys:
7
40
0
7
0
47
0
0
7
0
0
0
0
7
0
% K
% Leu:
14
0
14
60
0
7
74
14
0
87
0
20
14
7
14
% L
% Met:
0
0
7
7
0
0
7
0
47
0
0
0
0
0
0
% M
% Asn:
0
0
54
0
0
14
0
0
7
0
7
0
0
0
67
% N
% Pro:
14
0
0
7
20
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
14
0
0
7
20
0
0
7
0
0
7
54
0
0
% R
% Ser:
0
20
0
0
27
7
0
34
14
0
54
0
7
0
0
% S
% Thr:
0
0
0
7
7
0
0
34
14
0
7
7
0
14
14
% T
% Val:
7
0
7
7
7
0
7
0
0
0
7
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _