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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
30
Human Site:
S284
Identified Species:
47.14
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
S284
P
D
T
I
G
N
L
S
S
L
S
R
L
G
L
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
R255
N
R
L
S
A
I
P
R
S
L
A
K
C
S
A
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
S284
P
D
T
I
G
N
L
S
S
L
S
R
L
G
L
Dog
Lupus familis
XP_535013
582
64867
S284
P
D
T
I
G
N
L
S
S
L
S
R
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
S284
P
D
T
I
G
N
L
S
S
L
N
R
L
G
L
Rat
Rattus norvegicus
Q6AYI5
582
64902
S284
P
D
T
I
G
N
L
S
S
L
N
R
L
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
S284
P
E
T
I
G
N
L
S
S
L
N
R
L
G
L
Chicken
Gallus gallus
Q5F4C4
529
59144
N248
I
T
L
D
V
A
H
N
Q
L
E
H
L
P
E
Frog
Xenopus laevis
Q8AVI4
577
64082
S279
P
D
T
I
G
N
L
S
S
L
S
R
L
G
L
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
S276
G
L
R
Y
N
R
L
S
A
I
P
R
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
K344
P
D
S
I
G
N
L
K
S
L
V
R
L
G
M
Honey Bee
Apis mellifera
XP_396017
561
62921
L266
T
I
G
N
L
I
S
L
T
R
L
G
L
R
Y
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
N267
V
R
I
G
I
R
Y
N
K
I
R
C
I
P
S
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
L229
K
C
L
S
R
L
G
L
R
Y
N
R
L
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
S415
Q
E
L
G
N
M
E
S
M
I
N
L
D
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
86.6
13.3
100
20
N.A.
73.3
6.6
0
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
20
100
33.3
N.A.
86.6
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
7
0
7
0
0
0
14
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
7
7
0
0
% C
% Asp:
0
47
0
7
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
14
0
0
0
0
7
0
0
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
14
54
0
7
0
0
0
0
7
0
54
7
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
7
7
7
54
7
14
0
0
0
20
0
0
7
0
0
% I
% Lys:
7
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% K
% Leu:
0
7
27
0
7
7
60
14
0
67
7
7
74
14
47
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% M
% Asn:
7
0
0
7
14
54
0
14
0
0
34
0
0
0
0
% N
% Pro:
54
0
0
0
0
0
7
0
0
0
7
0
0
14
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
14
7
0
7
14
0
7
7
7
7
67
0
7
0
% R
% Ser:
0
0
7
14
0
0
7
60
60
0
27
0
7
7
14
% S
% Thr:
7
7
47
0
0
0
0
0
7
0
0
0
0
7
0
% T
% Val:
7
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _