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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
22.42
Human Site:
S67
Identified Species:
35.24
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
S67
A
Q
P
G
V
A
F
S
V
D
N
T
I
K
R
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
D56
D
A
K
D
G
K
K
D
S
S
A
A
Q
P
G
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
S67
A
Q
P
G
V
A
F
S
V
D
N
T
I
K
R
Dog
Lupus familis
XP_535013
582
64867
S67
A
Q
P
G
V
A
F
S
V
D
N
T
I
K
R
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
S67
A
Q
P
G
V
A
F
S
V
D
N
T
I
K
R
Rat
Rattus norvegicus
Q6AYI5
582
64902
S67
A
Q
P
G
V
A
F
S
V
D
N
T
I
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
S67
A
P
P
G
V
A
F
S
V
D
N
T
I
K
R
Chicken
Gallus gallus
Q5F4C4
529
59144
D49
E
P
K
T
K
G
K
D
A
K
D
G
K
K
D
Frog
Xenopus laevis
Q8AVI4
577
64082
R69
S
L
D
N
T
I
K
R
A
N
P
A
S
G
M
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
A67
T
R
K
K
S
S
N
A
E
V
I
K
E
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
K127
R
P
K
M
V
T
V
K
H
P
E
S
N
K
P
Honey Bee
Apis mellifera
XP_396017
561
62921
D67
S
K
S
N
D
Q
A
D
L
D
V
S
K
E
F
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
F67
R
K
D
L
L
K
E
F
H
K
C
K
E
A
Q
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
D30
K
Q
V
M
V
M
L
D
G
D
Q
V
K
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
N74
S
W
Y
G
V
S
C
N
S
R
G
S
I
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
93.3
6.6
0
0
N.A.
13.3
6.6
0
20
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
93.3
13.3
13.3
20
N.A.
20
40
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
7
0
0
0
40
7
7
14
0
7
14
0
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
14
7
7
0
0
27
0
54
7
0
0
0
7
% D
% Glu:
7
0
0
0
0
0
7
0
7
0
7
0
14
14
7
% E
% Phe:
0
0
0
0
0
0
40
7
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
47
7
7
0
0
7
0
7
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
47
0
0
% I
% Lys:
7
14
27
7
7
14
20
7
0
14
0
14
20
54
0
% K
% Leu:
0
7
0
7
7
0
7
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
14
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
14
0
0
7
7
0
7
40
0
7
0
7
% N
% Pro:
0
20
40
0
0
0
0
0
0
7
7
0
0
7
14
% P
% Gln:
0
40
0
0
0
7
0
0
0
0
7
0
7
0
7
% Q
% Arg:
14
7
0
0
0
0
0
7
0
7
0
0
0
7
40
% R
% Ser:
20
0
7
0
7
14
0
40
14
7
0
20
7
0
0
% S
% Thr:
7
0
0
7
7
7
0
0
0
0
0
40
0
0
0
% T
% Val:
0
0
7
0
60
0
7
0
40
7
7
7
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _