KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
31.21
Human Site:
T205
Identified Species:
49.05
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
T205
Y
L
R
F
N
R
I
T
T
V
E
K
D
I
K
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
S186
N
K
L
R
E
I
P
S
V
V
Y
R
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
T205
Y
L
R
F
N
R
I
T
T
V
E
K
D
I
K
Dog
Lupus familis
XP_535013
582
64867
T205
Y
L
R
F
N
R
I
T
T
V
E
K
D
I
K
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
T205
Y
L
R
F
N
R
I
T
T
V
E
K
D
I
K
Rat
Rattus norvegicus
Q6AYI5
582
64902
T205
Y
L
R
F
N
R
I
T
A
V
E
K
D
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
T205
Y
L
R
F
N
R
M
T
T
V
E
K
D
I
K
Chicken
Gallus gallus
Q5F4C4
529
59144
N179
R
M
L
D
L
R
H
N
K
L
R
E
I
P
S
Frog
Xenopus laevis
Q8AVI4
577
64082
T200
F
L
R
F
N
R
I
T
A
V
E
K
D
L
K
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
K207
S
I
R
E
N
K
I
K
Q
L
P
A
E
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
T265
Y
L
R
F
N
R
I
T
A
V
A
D
D
L
R
Honey Bee
Apis mellifera
XP_396017
561
62921
L197
N
I
R
N
L
T
N
L
T
M
L
S
L
R
E
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
N198
K
M
L
D
V
R
E
N
K
I
R
E
L
P
S
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
L160
T
K
L
T
M
L
S
L
R
E
N
K
I
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
G260
L
Y
E
N
Y
L
T
G
V
I
P
P
E
I
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
6.6
100
100
N.A.
100
80
N.A.
93.3
6.6
80
26.6
N.A.
66.6
13.3
6.6
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
93.3
N.A.
100
26.6
93.3
53.3
N.A.
80
33.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
0
7
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
0
0
0
0
0
0
7
54
7
0
% D
% Glu:
0
0
7
7
7
0
7
0
0
7
47
14
14
0
7
% E
% Phe:
7
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
7
54
0
0
14
0
0
14
47
0
% I
% Lys:
7
14
0
0
0
7
0
7
14
0
0
54
0
7
40
% K
% Leu:
7
54
27
0
14
14
0
14
0
14
7
0
20
14
0
% L
% Met:
0
14
0
0
7
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
14
0
0
14
60
0
7
14
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
14
7
0
14
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
7
0
67
7
0
67
0
0
7
0
14
7
0
7
14
% R
% Ser:
7
0
0
0
0
0
7
7
0
0
0
7
0
0
20
% S
% Thr:
7
0
0
7
0
7
7
54
40
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
14
60
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _