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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHOC2
All Species:
40
Human Site:
T485
Identified Species:
62.86
UniProt:
Q9UQ13
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ13
NP_031399.2
582
64888
T485
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Chimpanzee
Pan troglodytes
XP_001143999
536
59725
L440
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001087610
582
64886
T485
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Dog
Lupus familis
XP_535013
582
64867
T485
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Cat
Felis silvestris
Mouse
Mus musculus
O88520
582
64875
T485
L
T
N
N
Q
L
S
T
L
P
R
G
I
G
H
Rat
Rattus norvegicus
Q6AYI5
582
64902
T485
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513272
583
65345
T486
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Chicken
Gallus gallus
Q5F4C4
529
59144
S433
S
L
E
V
L
I
L
S
N
N
L
L
K
K
L
Frog
Xenopus laevis
Q8AVI4
577
64082
T480
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
T464
L
T
N
N
Q
L
T
T
L
P
R
G
I
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEK6
641
69354
M545
L
Q
T
N
Q
I
T
M
L
P
R
S
I
G
H
Honey Bee
Apis mellifera
XP_396017
561
62921
S465
L
Q
S
N
Q
V
T
S
L
P
R
A
I
G
H
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
T458
V
Q
S
N
K
I
L
T
L
P
R
S
I
G
N
Sea Urchin
Strong. purpuratus
XP_798409
510
57047
L414
Y
L
K
E
L
Q
K
L
S
V
Q
T
N
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LP24
1120
124085
V958
T
W
T
K
R
I
N
V
V
K
G
V
A
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.8
99.6
N.A.
98.4
97.9
N.A.
92.8
84.8
88.8
89
N.A.
53.8
60.4
53
58.4
Protein Similarity:
100
92
100
99.8
N.A.
99.4
98.9
N.A.
94.8
88.3
93.3
93.1
N.A.
68.8
76.2
71.3
71.8
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
100
0
100
100
N.A.
66.6
66.6
46.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
13.3
100
100
N.A.
73.3
86.6
80
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
14
54
7
74
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
67
% H
% Ile:
0
0
0
0
0
27
0
0
0
0
0
7
74
0
0
% I
% Lys:
0
0
7
7
7
0
7
0
0
7
0
0
7
7
0
% K
% Leu:
67
14
0
0
20
54
14
14
74
0
7
7
0
0
20
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
60
74
0
0
7
0
7
7
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
7
74
0
0
0
0
0
% P
% Gln:
0
20
0
7
67
7
0
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
7
74
0
0
0
0
% R
% Ser:
7
0
14
0
0
0
7
14
7
0
0
14
0
0
0
% S
% Thr:
14
54
14
0
0
7
67
60
0
0
0
7
0
0
0
% T
% Val:
7
0
0
7
0
7
0
7
7
7
0
7
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _