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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM3 All Species: 4.55
Human Site: S636 Identified Species: 7.69
UniProt: Q9UQ16 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ16 NP_001129599.1 869 97746 S636 A G V Y P D K S V A E N D E N
Chimpanzee Pan troglodytes XP_513998 866 97619 N633 P D K S V G N N K A E N D E N
Rhesus Macaque Macaca mulatta XP_001100178 863 97145 N630 P D K S V G N N K A E N D E N
Dog Lupus familis XP_850603 854 96173 S621 D S Q E D V D S W K A S L L R
Cat Felis silvestris
Mouse Mus musculus Q8BZ98 863 97172 N630 P D K S V G S N K T E N D E N
Rat Rattus norvegicus Q08877 869 97896 S636 A G V Y P D K S F T E N D E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515097 939 105893 N706 P D K S L G N N K A E S D E S
Chicken Gallus gallus XP_415501 861 96730 A628 V Y P E R V G A S E A E E N G
Frog Xenopus laevis NP_001093354 867 97947 K625 R A G V Y P E K D Q R E E E E
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 D461 L R F P K L H D A I V E V V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 E627 G V Y P E K Q E T Q E N G D E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P39055 830 93389 K600 K N I Y K D Y K Q L E L G C T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S944 808 89608 G578 V K S R S F L G R Q A N G I V
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 N527 D I H R A Y I N T N H P N F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 98.3 95 N.A. 96.7 97.1 N.A. 83.8 80.5 79.7 36.2 N.A. 66 N.A. 62.2 N.A.
Protein Similarity: 100 95.5 98.6 95.8 N.A. 98.1 98.6 N.A. 88 88.2 89.3 52.8 N.A. 78.1 N.A. 75.4 N.A.
P-Site Identity: 100 40 40 6.6 N.A. 33.3 86.6 N.A. 26.6 0 6.6 0 N.A. 13.3 N.A. 20 N.A.
P-Site Similarity: 100 46.6 46.6 13.3 N.A. 40 86.6 N.A. 46.6 13.3 20 0 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.5 36 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 53 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 0 8 0 0 8 8 29 22 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 15 29 0 0 8 22 8 8 8 0 0 0 43 8 0 % D
% Glu: 0 0 0 15 8 0 8 8 0 8 58 22 15 50 15 % E
% Phe: 0 0 8 0 0 8 0 0 8 0 0 0 0 8 0 % F
% Gly: 8 15 8 0 0 29 8 8 0 0 0 0 22 0 8 % G
% His: 0 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 8 0 0 8 0 0 0 8 0 % I
% Lys: 8 8 29 0 15 8 15 15 29 8 0 0 0 0 0 % K
% Leu: 8 0 0 0 8 8 8 0 0 8 0 8 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 22 36 0 8 0 50 8 8 36 % N
% Pro: 29 0 8 15 15 8 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 8 0 0 0 8 0 8 22 0 0 0 0 0 % Q
% Arg: 8 8 0 15 8 0 0 0 8 0 8 0 0 0 8 % R
% Ser: 0 8 8 29 8 0 8 22 8 0 0 15 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 15 15 0 0 0 0 15 % T
% Val: 15 8 15 8 22 15 0 0 8 0 8 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 8 8 22 8 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _