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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM3 All Species: 4.55
Human Site: T438 Identified Species: 7.69
UniProt: Q9UQ16 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ16 NP_001129599.1 869 97746 T438 V I Q E L I N T V K K C T K K
Chimpanzee Pan troglodytes XP_513998 866 97619 I435 L K S V D L V I Q E L I N T V
Rhesus Macaque Macaca mulatta XP_001100178 863 97145 I432 L K S V D L V I Q E L I N T V
Dog Lupus familis XP_850603 854 96173 P423 Q I V K L K G P S L K S V D L
Cat Felis silvestris
Mouse Mus musculus Q8BZ98 863 97172 M432 L K S V D L V M Q E L I N T V
Rat Rattus norvegicus Q08877 869 97896 T438 V M Q E L I N T V K K C T K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515097 939 105893 M508 L K S V D L V M Q E L I N T V
Chicken Gallus gallus XP_415501 861 96730 M430 P C L K C V D M V I S E L I N
Frog Xenopus laevis NP_001093354 867 97947 C427 L K E P C L K C V D M V I Q E
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 D263 S V A D S I R D E H G F L Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 Q429 K C V D L V V Q E L S V V V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P39055 830 93389 R402 I R N I H G I R V G L F T P D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S944 808 89608 E380 E A Y S S L L E G K S E E M S
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 R329 Q T L L S H I R D K L P D I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 98.3 95 N.A. 96.7 97.1 N.A. 83.8 80.5 79.7 36.2 N.A. 66 N.A. 62.2 N.A.
Protein Similarity: 100 95.5 98.6 95.8 N.A. 98.1 98.6 N.A. 88 88.2 89.3 52.8 N.A. 78.1 N.A. 75.4 N.A.
P-Site Identity: 100 0 0 20 N.A. 0 86.6 N.A. 0 6.6 6.6 13.3 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 20 20 26.6 N.A. 20 100 N.A. 20 26.6 40 33.3 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.5 36 N.A.
Protein Similarity: N.A. N.A. N.A. 52.4 53 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 15 0 0 15 0 0 8 0 0 0 15 0 0 0 % C
% Asp: 0 0 0 15 29 0 8 8 8 8 0 0 8 8 8 % D
% Glu: 8 0 8 15 0 0 0 8 15 29 0 15 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 0 8 8 8 0 0 0 0 % G
% His: 0 0 0 0 8 8 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 15 0 8 0 22 15 15 0 8 0 29 8 15 0 % I
% Lys: 8 36 0 15 0 8 8 0 0 29 22 0 0 15 22 % K
% Leu: 36 0 15 8 29 43 8 0 0 15 43 0 15 0 8 % L
% Met: 0 8 0 0 0 0 0 22 0 0 8 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 15 0 0 0 0 0 29 0 8 % N
% Pro: 8 0 0 8 0 0 0 8 0 0 0 8 0 8 0 % P
% Gln: 15 0 15 0 0 0 0 8 29 0 0 0 0 15 0 % Q
% Arg: 0 8 0 0 0 0 8 15 0 0 0 0 0 0 15 % R
% Ser: 8 0 29 8 22 0 0 0 8 0 22 8 0 0 8 % S
% Thr: 0 8 0 0 0 0 0 15 0 0 0 0 22 29 0 % T
% Val: 15 8 15 29 0 15 36 0 36 0 0 15 15 8 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _