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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
19.09
Human Site:
S353
Identified Species:
35
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S353
A
M
P
A
H
S
R
S
H
S
W
D
D
K
T
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S353
A
M
P
A
H
S
R
S
R
S
W
D
D
K
T
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S353
A
M
P
A
H
S
R
S
R
S
W
D
D
K
T
Dog
Lupus familis
XP_547491
836
92524
S353
A
M
P
A
Q
S
R
S
Q
S
W
N
D
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
P343
E
Q
I
D
D
Y
S
P
D
T
M
P
A
H
S
Rat
Rattus norvegicus
NP_001100668
836
91871
S352
T
M
P
A
H
S
R
S
H
S
W
N
D
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
S353
A
P
P
C
Q
P
R
S
R
G
W
N
D
P
A
Chicken
Gallus gallus
XP_419550
807
90135
A313
D
P
E
T
L
L
Y
A
G
R
Y
P
F
D
S
Frog
Xenopus laevis
Q9W6K2
734
82213
L276
E
G
Y
I
E
G
F
L
R
A
N
N
T
F
L
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
R337
L
D
I
N
T
M
Q
R
I
D
D
F
N
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
I274
L
E
V
D
D
D
Y
I
E
N
F
M
K
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
T277
S
F
K
R
A
L
L
T
F
K
H
Q
R
V
Y
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
V244
L
I
T
A
M
K
L
V
R
R
F
N
T
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
0
80
N.A.
40
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
13.3
86.6
N.A.
46.6
20
13.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
47
8
0
0
8
0
8
0
0
8
8
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
16
16
8
0
0
8
8
8
24
47
8
8
% D
% Glu:
16
8
8
0
8
0
0
0
8
0
0
0
0
0
16
% E
% Phe:
0
8
0
0
0
0
8
0
8
0
16
8
8
8
0
% F
% Gly:
0
8
0
0
0
8
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
31
0
0
0
16
0
8
0
0
8
0
% H
% Ile:
0
8
16
8
0
0
0
8
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
8
0
0
0
8
0
0
8
39
0
% K
% Leu:
24
0
0
0
8
16
16
8
0
0
0
0
0
0
8
% L
% Met:
0
39
0
0
8
8
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
8
39
8
0
0
% N
% Pro:
0
16
47
0
0
8
0
8
0
0
0
16
0
16
0
% P
% Gln:
0
8
0
0
16
0
8
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
47
8
39
16
0
0
8
0
0
% R
% Ser:
8
0
0
0
0
39
8
47
0
39
0
0
0
0
16
% S
% Thr:
8
0
8
8
8
0
0
8
0
8
0
0
16
0
31
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
16
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _