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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
10.91
Human Site:
S381
Identified Species:
20
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S381
N
Y
S
P
R
P
E
S
G
T
V
S
D
A
P
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S381
N
Y
S
P
R
P
E
S
G
I
V
S
D
A
P
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S381
N
Y
S
P
R
P
E
S
G
I
V
S
D
A
P
Dog
Lupus familis
XP_547491
836
92524
L381
N
Y
C
P
R
L
E
L
D
I
V
S
D
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
H371
P
G
T
N
S
I
W
H
K
N
Y
C
P
R
L
Rat
Rattus norvegicus
NP_001100668
836
91871
V380
N
Y
C
P
R
L
E
V
N
S
V
S
H
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
E381
K
N
Y
L
S
T
P
E
A
A
A
A
P
G
P
Chicken
Gallus gallus
XP_419550
807
90135
Y341
T
M
E
Q
I
D
N
Y
N
P
D
T
A
Q
P
Frog
Xenopus laevis
Q9W6K2
734
82213
D304
P
L
N
P
Y
G
N
D
V
N
P
E
E
L
N
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
K365
S
W
N
D
R
C
D
K
T
A
T
T
Q
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
A302
R
R
M
Q
R
L
C
A
L
E
D
Y
E
T
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
S305
S
D
N
L
G
E
D
S
D
F
V
G
P
S
M
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
E272
I
P
D
T
Y
I
N
E
Y
E
A
A
V
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
60
N.A.
0
60
N.A.
6.6
6.6
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
60
N.A.
6.6
66.6
N.A.
13.3
13.3
20
46.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
16
16
16
8
47
8
% A
% Cys:
0
0
16
0
0
8
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
8
0
8
16
8
16
0
16
0
31
0
8
% D
% Glu:
0
0
8
0
0
8
39
16
0
16
0
8
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
8
0
0
24
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
8
16
0
0
0
24
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
8
0
16
0
24
0
8
8
0
0
0
0
16
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
39
8
24
8
0
0
24
0
16
16
0
0
0
0
8
% N
% Pro:
16
8
0
47
0
24
8
0
0
8
8
0
24
0
47
% P
% Gln:
0
0
0
16
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
8
8
0
0
54
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
16
0
24
0
16
0
0
31
0
8
0
39
0
8
8
% S
% Thr:
8
0
8
8
0
8
0
0
8
8
8
16
0
8
8
% T
% Val:
0
0
0
0
0
0
0
8
8
0
47
0
8
0
0
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
39
8
0
16
0
0
8
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _