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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXO1 All Species: 15.15
Human Site: S414 Identified Species: 27.78
UniProt: Q9UQ84 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQ84 NP_003677.3 846 94103 S414 G L N L P R K S S I V K R P R
Chimpanzee Pan troglodytes XP_001160902 846 94086 S414 G L N L P R K S S I V K R P R
Rhesus Macaque Macaca mulatta XP_001093427 846 94132 S414 G L N L P R K S S I V K R P R
Dog Lupus familis XP_547491 836 92524 S414 G L N L P R K S S T V K R P R
Cat Felis silvestris
Mouse Mus musculus Q9QZ11 837 92003 T404 G L K Q V I S T K G L N L P R
Rat Rattus norvegicus NP_001100668 836 91871 P413 G L N L P R K P C V L K R P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514118 820 89598 K414 K A L N L P S K P L F V K R P
Chicken Gallus gallus XP_419550 807 90135 L374 I W S K D Y K L G P S T D D A
Frog Xenopus laevis Q9W6K2 734 82213 Q337 M D I N T R K Q I D D Y N P D
Zebra Danio Brachydanio rerio Q803U7 806 88576 R398 P K R P P P T R G K E R I V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24558 732 83163 N335 H L A L G N L N P F S M K R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L6Z7 735 82230 V338 L P F Q A E S V T P K L A V D
Baker's Yeast Sacchar. cerevisiae P39875 702 80144 D305 E I P L Y L K D T E S K R K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.5 82 N.A. 72.6 75.5 N.A. 60.8 58.1 49.2 48.1 N.A. 30.1 N.A. N.A. N.A.
Protein Similarity: 100 99.1 97 88 N.A. 81.8 82.8 N.A. 72.6 71.5 62.1 62.4 N.A. 48.3 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 26.6 73.3 N.A. 0 6.6 20 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 40 86.6 N.A. 13.3 13.3 20 13.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.3 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 0 0 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 8 0 8 8 0 8 8 16 % D
% Glu: 8 0 0 0 0 8 0 0 0 8 8 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 47 0 0 0 8 0 0 0 16 8 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 8 0 0 8 24 0 0 8 0 0 % I
% Lys: 8 8 8 8 0 0 62 8 8 8 8 47 16 8 0 % K
% Leu: 8 54 8 54 8 8 8 8 0 8 16 8 8 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 39 16 0 8 0 8 0 0 0 8 8 0 0 % N
% Pro: 8 8 8 8 47 16 0 8 16 16 0 0 0 54 8 % P
% Gln: 0 0 0 16 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 47 0 8 0 0 0 8 47 16 54 % R
% Ser: 0 0 8 0 0 0 24 31 31 0 24 0 0 0 8 % S
% Thr: 0 0 0 0 8 0 8 8 16 8 0 8 0 0 0 % T
% Val: 0 0 0 0 8 0 0 8 0 8 31 8 0 16 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _