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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
12.12
Human Site:
S452
Identified Species:
22.22
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S452
N
S
S
E
G
N
K
S
L
S
F
S
E
V
F
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S452
N
S
S
E
G
N
K
S
L
S
S
S
E
V
F
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S452
N
S
Y
E
G
N
I
S
L
S
S
S
E
V
F
Dog
Lupus familis
XP_547491
836
92524
S452
N
N
C
E
G
P
K
S
L
N
S
S
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
E442
S
V
S
K
K
I
K
E
N
G
C
G
D
G
T
Rat
Rattus norvegicus
NP_001100668
836
91871
P451
S
C
G
N
G
T
S
P
N
S
S
E
M
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
R452
E
D
P
G
P
E
G
R
G
P
R
K
A
S
A
Chicken
Gallus gallus
XP_419550
807
90135
L412
L
K
L
P
G
K
E
L
F
T
K
R
Q
R
S
Frog
Xenopus laevis
Q9W6K2
734
82213
K375
T
D
S
I
W
Y
T
K
S
E
P
C
K
T
T
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
Y436
V
D
D
L
L
E
Q
Y
T
A
G
V
K
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
E373
W
Q
T
N
F
Q
S
E
N
T
H
T
P
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
C376
N
L
L
T
K
Y
F
C
F
A
S
V
E
A
K
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
L343
D
I
D
H
H
L
H
L
K
I
A
Q
G
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
80
53.3
N.A.
13.3
13.3
N.A.
0
6.6
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
73.3
N.A.
33.3
20
N.A.
0
26.6
13.3
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
16
8
0
8
8
8
% A
% Cys:
0
8
8
0
0
0
0
8
0
0
8
8
0
0
0
% C
% Asp:
8
24
16
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
31
0
16
8
16
0
8
0
8
39
0
0
% E
% Phe:
0
0
0
0
8
0
8
0
16
0
8
0
0
0
24
% F
% Gly:
0
0
8
8
47
0
8
0
8
8
8
8
8
8
0
% G
% His:
0
0
0
8
8
0
8
0
0
0
8
0
0
0
8
% H
% Ile:
0
8
0
8
0
8
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
16
8
31
8
8
0
8
8
16
8
16
% K
% Leu:
8
8
16
8
8
8
0
16
31
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
39
8
0
16
0
24
0
0
24
8
0
0
0
0
0
% N
% Pro:
0
0
8
8
8
8
0
8
0
8
8
0
8
0
0
% P
% Gln:
0
8
0
0
0
8
8
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
8
0
16
0
% R
% Ser:
16
24
31
0
0
0
16
31
8
31
39
31
0
16
8
% S
% Thr:
8
0
8
8
0
8
8
0
8
16
0
8
0
8
16
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
16
0
24
8
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
16
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _