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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
14.85
Human Site:
S494
Identified Species:
27.22
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S494
L
Q
R
K
N
E
E
S
G
A
V
V
V
P
G
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S494
L
Q
R
K
N
E
E
S
G
A
V
V
V
P
G
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S494
L
Q
R
K
N
E
E
S
G
A
V
V
V
P
G
Dog
Lupus familis
XP_547491
836
92524
S494
L
Q
R
K
N
E
E
S
G
A
V
V
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
F484
M
R
N
K
F
A
T
F
L
Q
R
R
N
E
E
Rat
Rattus norvegicus
NP_001100668
836
91871
G493
Q
R
R
N
E
E
C
G
A
I
V
V
P
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
V494
N
Q
A
D
G
A
V
V
V
P
G
T
R
S
R
Chicken
Gallus gallus
XP_419550
807
90135
A454
Q
S
Q
K
S
I
S
A
I
Q
S
I
D
S
S
Frog
Xenopus laevis
Q9W6K2
734
82213
S417
V
S
D
T
D
L
I
S
Q
Y
S
F
S
K
N
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
R478
G
P
F
R
P
R
N
R
F
A
T
L
L
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
E415
L
E
Q
A
K
Q
T
E
A
E
L
F
N
M
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
S418
P
D
L
D
A
L
S
S
Q
T
T
N
E
S
P
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
E385
K
T
N
T
T
N
S
E
A
K
V
K
P
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
26.6
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
33.3
N.A.
6.6
33.3
20
26.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
16
0
8
24
39
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
16
8
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
8
39
31
16
0
8
0
0
8
8
16
% E
% Phe:
0
0
8
0
8
0
0
8
8
0
0
16
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
8
31
0
8
0
0
8
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
8
8
0
8
0
8
0
% I
% Lys:
8
0
0
47
8
0
0
0
0
8
0
8
0
8
0
% K
% Leu:
39
0
8
0
0
16
0
0
8
0
8
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
16
8
31
8
8
0
0
0
0
8
16
0
8
% N
% Pro:
8
8
0
0
8
0
0
0
0
8
0
0
16
31
8
% P
% Gln:
16
39
16
0
0
8
0
0
16
16
0
0
0
8
0
% Q
% Arg:
0
16
39
8
0
8
0
8
0
0
8
8
8
0
8
% R
% Ser:
0
16
0
0
8
0
24
47
0
0
16
0
8
24
8
% S
% Thr:
0
8
0
16
8
0
16
0
0
8
16
8
0
0
8
% T
% Val:
8
0
0
0
0
0
8
8
8
0
47
39
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _