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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
12.12
Human Site:
S649
Identified Species:
22.22
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S649
S
L
P
E
N
N
M
S
D
V
S
Q
L
K
S
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S649
S
L
P
E
N
N
M
S
D
V
S
Q
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S650
S
L
P
E
I
S
M
S
D
V
S
Q
L
K
S
Dog
Lupus familis
XP_547491
836
92524
E651
R
S
D
E
S
G
D
E
A
P
P
S
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
V640
C
L
P
E
A
S
A
V
V
T
D
R
C
D
S
Rat
Rattus norvegicus
NP_001100668
836
91871
D653
S
K
S
G
T
L
G
D
K
S
Q
S
L
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
S652
P
A
A
A
E
R
L
S
P
G
S
R
N
S
S
Chicken
Gallus gallus
XP_419550
807
90135
V607
Q
A
D
D
S
N
G
V
Q
A
E
S
G
A
V
Frog
Xenopus laevis
Q9W6K2
734
82213
L569
C
F
T
W
S
G
S
L
D
S
E
S
S
P
T
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
S632
A
G
P
G
L
S
L
S
S
S
P
V
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
N567
C
K
D
I
P
G
K
N
P
I
R
Q
R
C
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
N570
T
I
N
T
H
K
I
N
H
Q
I
N
E
E
E
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
D537
G
N
E
I
Y
N
T
D
D
D
G
D
G
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
6.6
N.A.
26.6
13.3
N.A.
20
6.6
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
40
13.3
N.A.
33.3
20
20
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
8
8
0
8
0
8
8
0
0
0
8
8
% A
% Cys:
24
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
24
8
0
0
8
16
39
8
8
8
0
16
0
% D
% Glu:
0
0
8
39
8
0
0
8
0
0
16
0
16
8
16
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
16
0
24
16
0
0
8
8
0
16
8
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
16
8
0
8
0
0
8
8
0
0
0
0
% I
% Lys:
0
16
0
0
0
8
8
0
8
0
0
0
0
24
0
% K
% Leu:
0
31
0
0
8
8
16
8
0
0
0
0
31
8
0
% L
% Met:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
16
31
0
16
0
0
0
8
8
0
0
% N
% Pro:
8
0
39
0
8
0
0
0
16
8
16
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
8
31
0
0
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
0
8
16
16
0
0
% R
% Ser:
31
8
8
0
24
24
8
39
8
24
31
31
8
8
54
% S
% Thr:
8
0
8
8
8
0
8
0
0
8
0
0
0
0
16
% T
% Val:
0
0
0
0
0
0
0
16
8
24
0
8
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _