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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
14.55
Human Site:
S674
Identified Species:
26.67
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S674
L
R
E
E
A
C
S
S
Q
S
Q
E
S
G
E
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S674
L
R
E
G
A
C
S
S
Q
S
Q
E
S
G
E
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
S675
L
R
E
G
A
C
S
S
Q
C
Q
E
S
G
E
Dog
Lupus familis
XP_547491
836
92524
N676
A
L
S
P
H
S
L
N
A
S
K
L
S
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
S665
P
L
H
E
L
G
C
S
S
R
S
Q
E
S
M
Rat
Rattus norvegicus
NP_001100668
836
91871
N678
I
D
S
T
C
S
L
N
T
S
S
L
S
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
S677
E
D
S
P
S
E
E
S
D
C
R
V
R
E
S
Chicken
Gallus gallus
XP_419550
807
90135
S632
L
I
E
P
Q
C
F
S
Q
S
Q
K
S
V
E
Frog
Xenopus laevis
Q9W6K2
734
82213
P594
Q
K
F
H
R
T
T
P
Y
M
Q
N
E
A
E
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
F657
P
S
Q
D
S
A
Y
F
S
Q
S
S
S
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
L592
D
T
T
A
S
S
L
L
E
S
Q
D
K
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
I595
F
S
T
P
E
N
V
I
P
L
S
S
I
A
I
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
T562
R
V
P
T
S
S
T
T
S
F
P
G
S
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
13.3
N.A.
13.3
13.3
N.A.
6.6
60
13.3
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
26.6
N.A.
20
26.6
N.A.
20
66.6
26.6
26.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
24
8
0
0
8
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
8
31
8
0
0
16
0
0
0
0
0
% C
% Asp:
8
16
0
8
0
0
0
0
8
0
0
8
0
0
0
% D
% Glu:
8
0
31
16
8
8
8
0
8
0
0
24
16
8
39
% E
% Phe:
8
0
8
0
0
0
8
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
16
0
8
0
0
0
0
0
8
0
31
0
% G
% His:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
0
0
0
8
8
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
8
8
8
0
0
% K
% Leu:
31
16
0
0
8
0
24
8
0
8
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
16
0
0
0
8
0
0
0
% N
% Pro:
16
0
8
31
0
0
0
8
8
0
8
0
0
0
16
% P
% Gln:
8
0
8
0
8
0
0
0
31
8
47
8
0
16
8
% Q
% Arg:
8
24
0
0
8
0
0
0
0
8
8
0
8
0
0
% R
% Ser:
0
16
24
0
31
31
24
47
24
47
31
16
62
16
16
% S
% Thr:
0
8
16
16
0
8
16
8
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _