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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXO1
All Species:
8.18
Human Site:
S749
Identified Species:
15
UniProt:
Q9UQ84
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ84
NP_003677.3
846
94103
S749
Y
K
S
S
S
A
D
S
L
S
T
T
K
I
K
Chimpanzee
Pan troglodytes
XP_001160902
846
94086
S749
Y
K
S
S
S
A
D
S
L
S
T
T
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001093427
846
94132
L750
K
S
S
S
A
D
S
L
S
A
T
K
I
K
P
Dog
Lupus familis
XP_547491
836
92524
A751
K
P
L
V
P
A
R
A
S
G
L
S
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ11
837
92003
S740
C
R
S
S
S
M
D
S
F
S
T
T
K
I
K
Rat
Rattus norvegicus
NP_001100668
836
91871
V753
K
P
L
V
P
A
R
V
S
G
L
S
K
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514118
820
89598
H752
A
G
P
K
G
F
G
H
D
V
E
N
E
P
G
Chicken
Gallus gallus
XP_419550
807
90135
G707
L
R
K
S
S
S
V
G
S
H
I
V
T
K
L
Frog
Xenopus laevis
Q9W6K2
734
82213
P669
P
E
P
K
G
S
A
P
K
S
K
V
P
G
L
Zebra Danio
Brachydanio rerio
Q803U7
806
88576
R732
I
E
T
S
A
P
A
R
A
S
G
L
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24558
732
83163
R667
D
S
C
S
S
D
Q
R
A
S
S
T
S
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Z7
735
82230
K670
H
Y
S
E
I
A
E
K
S
V
E
R
F
V
S
Baker's Yeast
Sacchar. cerevisiae
P39875
702
80144
R637
I
T
Q
R
P
S
L
R
K
S
L
I
G
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
82
N.A.
72.6
75.5
N.A.
60.8
58.1
49.2
48.1
N.A.
30.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97
88
N.A.
81.8
82.8
N.A.
72.6
71.5
62.1
62.4
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
13.3
N.A.
73.3
13.3
N.A.
0
13.3
6.6
20
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
26.6
N.A.
80
20
N.A.
6.6
26.6
20
46.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
39
16
8
16
8
0
0
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
16
24
0
8
0
0
0
0
0
0
% D
% Glu:
0
16
0
8
0
0
8
0
0
0
16
0
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
16
0
8
8
0
16
8
0
8
8
8
% G
% His:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
16
0
0
0
8
0
0
0
0
0
8
8
8
24
0
% I
% Lys:
24
16
8
16
0
0
0
8
16
0
8
8
39
31
31
% K
% Leu:
8
0
16
0
0
0
8
8
16
0
24
8
0
0
16
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
16
16
0
24
8
0
8
0
0
0
0
8
8
24
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
0
8
0
0
16
24
0
0
0
8
8
8
8
% R
% Ser:
0
16
39
54
39
24
8
24
39
54
8
16
8
8
16
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
31
31
8
0
0
% T
% Val:
0
0
0
16
0
0
8
8
0
16
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _